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PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.
Cancer Discov. 2019 Sep;9(9):1306-1323. doi: 10.1158/2159-8290.CD-18-0083. Epub 2019 Jun 19.
Cancer Discov. 2019.
PMID: 31217297
Free PMC article.
Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.
Davidson L, Maccario H, Perera NM, Yang X, Spinelli L, Tibarewal P, Glancy B, Gray A, Weijer CJ, Downes CP, Leslie NR.
Davidson L, et al. Among authors: tibarewal p.
Oncogene. 2010 Feb 4;29(5):687-97. doi: 10.1038/onc.2009.384. Epub 2009 Nov 16.
Oncogene. 2010.
PMID: 19915616
Free PMC article.
Item in Clipboard
The PTEN and Myotubularin phosphoinositide 3-phosphatases: linking lipid signalling to human disease.
Davies EM, Sheffield DA, Tibarewal P, Fedele CG, Mitchell CA, Leslie NR.
Davies EM, et al. Among authors: tibarewal p.
Subcell Biochem. 2012;58:281-336. doi: 10.1007/978-94-007-3012-0_8.
Subcell Biochem. 2012.
PMID: 22403079
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Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells.
Hawley SA, Ross FA, Gowans GJ, Tibarewal P, Leslie NR, Hardie DG.
Hawley SA, et al. Among authors: tibarewal p.
Biochem J. 2014 Apr 15;459(2):275-87. doi: 10.1042/BJ20131344.
Biochem J. 2014.
PMID: 24467442
Free PMC article.
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Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.
Tibarewal P, Spinelli L, Maccario H, Leslie NR.
Tibarewal P, et al.
Adv Biol Regul. 2024 Jan;91:100989. doi: 10.1016/j.jbior.2023.100989. Epub 2023 Oct 4.
Adv Biol Regul. 2024.
PMID: 37839992
Free article.
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Indirect mechanisms of carcinogenesis via downregulation of PTEN function.
Leslie NR, Spinelli L, Tibarewal P, Zilidis G, Weerasinghe N, Lim JC, Maccario H, Downes CP.
Leslie NR, et al. Among authors: tibarewal p.
Adv Enzyme Regul. 2010;50(1):112-8. doi: 10.1016/j.advenzreg.2009.10.015. Epub 2009 Nov 4.
Adv Enzyme Regul. 2010.
PMID: 19895830
Review.
No abstract available.
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PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity.
Tibarewal P, Zilidis G, Spinelli L, Schurch N, Maccario H, Gray A, Perera NM, Davidson L, Barton GJ, Leslie NR.
Tibarewal P, et al.
Sci Signal. 2012 Feb 28;5(213):ra18. doi: 10.1126/scisignal.2002138.
Sci Signal. 2012.
PMID: 22375056
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Long-term treatment of cancer-prone germline PTEN mutant mice with low-dose rapamycin extends lifespan and delays tumour development.
Tibarewal P, Rathbone V, Constantinou G, Pearce W, Adil M, Varyova Z, Folkes L, Hampson A, Classen GAE, Alves A, Carvalho S, Scudamore CL, Vanhaesebroeck B.
Tibarewal P, et al.
J Pathol. 2022 Dec;258(4):382-394. doi: 10.1002/path.6009. Epub 2022 Oct 31.
J Pathol. 2022.
PMID: 36073856
Free PMC article.
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