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Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling.
Gunner G, Cheadle L, Johnson KM, Ayata P, Badimon A, Mondo E, Nagy MA, Liu L, Bemiller SM, Kim KW, Lira SA, Lamb BT, Tapper AR, Ransohoff RM, Greenberg ME, Schaefer A, Schafer DP. Gunner G, et al. Among authors: lamb bt. Nat Neurosci. 2019 Jul;22(7):1075-1088. doi: 10.1038/s41593-019-0419-y. Epub 2019 Jun 17. Nat Neurosci. 2019. PMID: 31209379 Free PMC article.
TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.
Jay TR, Miller CM, Cheng PJ, Graham LC, Bemiller S, Broihier ML, Xu G, Margevicius D, Karlo JC, Sousa GL, Cotleur AC, Butovsky O, Bekris L, Staugaitis SM, Leverenz JB, Pimplikar SW, Landreth GE, Howell GR, Ransohoff RM, Lamb BT. Jay TR, et al. Among authors: lamb bt. J Exp Med. 2015 Mar 9;212(3):287-95. doi: 10.1084/jem.20142322. Epub 2015 Mar 2. J Exp Med. 2015. PMID: 25732305 Free PMC article.
Loss of tau rescues inflammation-mediated neurodegeneration.
Maphis N, Xu G, Kokiko-Cochran ON, Cardona AE, Ransohoff RM, Lamb BT, Bhaskar K. Maphis N, et al. Among authors: lamb bt. Front Neurosci. 2015 Jun 3;9:196. doi: 10.3389/fnins.2015.00196. eCollection 2015. Front Neurosci. 2015. PMID: 26089772 Free PMC article.
143 results