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Hormonal and spatial control of SUMOylation in the human and mouse adrenal cortex.
Dumontet T, Sahut-Barnola I, Dufour D, Lefrançois-Martinez AM, Berthon A, Montanier N, Ragazzon B, Djari C, Pointud JC, Roucher-Boulez F, Batisse-Lignier M, Tauveron I, Bertherat J, Val P, Martinez A. Dumontet T, et al. FASEB J. 2019 Sep;33(9):10218-10230. doi: 10.1096/fj.201900557R. Epub 2019 Jun 17. FASEB J. 2019. PMID: 31208233 Free article.
Analysis of the role of Igf2 in adrenal tumour development in transgenic mouse models.
Drelon C, Berthon A, Ragazzon B, Tissier F, Bandiera R, Sahut-Barnola I, de Joussineau C, Batisse-Lignier M, Lefrançois-Martinez AM, Bertherat J, Martinez A, Val P. Drelon C, et al. PLoS One. 2012;7(8):e44171. doi: 10.1371/journal.pone.0044171. Epub 2012 Aug 28. PLoS One. 2012. PMID: 22952916 Free PMC article.
WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production.
Berthon A, Drelon C, Ragazzon B, Boulkroun S, Tissier F, Amar L, Samson-Couterie B, Zennaro MC, Plouin PF, Skah S, Plateroti M, Lefèbvre H, Sahut-Barnola I, Batisse-Lignier M, Assié G, Lefrançois-Martinez AM, Bertherat J, Martinez A, Val P. Berthon A, et al. Hum Mol Genet. 2014 Feb 15;23(4):889-905. doi: 10.1093/hmg/ddt484. Epub 2013 Oct 1. Hum Mol Genet. 2014. PMID: 24087794
mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD).
de Joussineau C, Sahut-Barnola I, Tissier F, Dumontet T, Drelon C, Batisse-Lignier M, Tauveron I, Pointud JC, Lefrançois-Martinez AM, Stratakis CA, Bertherat J, Val P, Martinez A. de Joussineau C, et al. Hum Mol Genet. 2014 Oct 15;23(20):5418-28. doi: 10.1093/hmg/ddu265. Epub 2014 May 27. Hum Mol Genet. 2014. PMID: 24865460 Free PMC article.
EZH2 is overexpressed in adrenocortical carcinoma and is associated with disease progression.
Drelon C, Berthon A, Mathieu M, Ragazzon B, Kuick R, Tabbal H, Septier A, Rodriguez S, Batisse-Lignier M, Sahut-Barnola I, Dumontet T, Pointud JC, Lefrançois-Martinez AM, Baron S, Giordano TJ, Bertherat J, Martinez A, Val P. Drelon C, et al. Hum Mol Genet. 2016 Jul 1;25(13):2789-2800. doi: 10.1093/hmg/ddw136. Epub 2016 May 5. Hum Mol Genet. 2016. PMID: 27149985 Free PMC article.
Mouse Models Recapitulating Human Adrenocortical Tumors: What Is Lacking?
Leccia F, Batisse-Lignier M, Sahut-Barnola I, Val P, Lefrançois-Martinez AM, Martinez A. Leccia F, et al. Front Endocrinol (Lausanne). 2016 Jul 15;7:93. doi: 10.3389/fendo.2016.00093. eCollection 2016. Front Endocrinol (Lausanne). 2016. PMID: 27471492 Free PMC article. Review.
PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development.
Drelon C, Berthon A, Sahut-Barnola I, Mathieu M, Dumontet T, Rodriguez S, Batisse-Lignier M, Tabbal H, Tauveron I, Lefrançois-Martinez AM, Pointud JC, Gomez-Sanchez CE, Vainio S, Shan J, Sacco S, Schedl A, Stratakis CA, Martinez A, Val P. Drelon C, et al. Nat Commun. 2016 Sep 14;7:12751. doi: 10.1038/ncomms12751. Nat Commun. 2016. PMID: 27624192 Free PMC article.
33 results