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Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis.
Yang YM, Noureddin M, Liu C, Ohashi K, Kim SY, Ramnath D, Powell EE, Sweet MJ, Roh YS, Hsin IF, Deng N, Liu Z, Liang J, Mena E, Shouhed D, Schwabe RF, Jiang D, Lu SC, Noble PW, Seki E. Yang YM, et al. Among authors: ramnath d. Sci Transl Med. 2019 Jun 12;11(496):eaat9284. doi: 10.1126/scitranslmed.aat9284. Sci Transl Med. 2019. PMID: 31189722 Free PMC article.
Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic type 2 inflammation.
Loh Z, Fitzsimmons RL, Reid RC, Ramnath D, Clouston A, Gupta PK, Irvine KM, Powell EE, Schroder K, Stow JL, Sweet MJ, Fairlie DP, Iyer A. Loh Z, et al. Among authors: ramnath d. Br J Pharmacol. 2019 Oct;176(19):3775-3790. doi: 10.1111/bph.14768. Epub 2019 Aug 17. Br J Pharmacol. 2019. PMID: 31236923 Free PMC article.
Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease.
Jouffe C, Weger BD, Martin E, Atger F, Weger M, Gobet C, Ramnath D, Charpagne A, Morin-Rivron D, Powell EE, Sweet MJ, Masoodi M, Uhlenhaut NH, Gachon F. Jouffe C, et al. Among authors: ramnath d. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2200083119. doi: 10.1073/pnas.2200083119. Epub 2022 Mar 1. Proc Natl Acad Sci U S A. 2022. PMID: 35238641 Free PMC article.
15 results