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The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia.
Angenendt L, Bormann E, Pabst C, Alla V, Görlich D, Braun L, Dohlich K, Schwöppe C, Bohlander SK, Arteaga MF, Wethmar K, Hartmann W, Angenendt A, Kessler T, Mesters RM, Stelljes M, Rothenberg-Thurley M, Spiekermann K, Hébert J, Sauvageau G, Valk PJM, Löwenberg B, Serve H, Müller-Tidow C, Lenz G, Wörmann BJ, Sauerland MC, Hiddemann W, Berdel WE, Krug U, Metzeler KH, Mikesch JH, Herold T, Schliemann C. Angenendt L, et al. Among authors: arteaga mf. Leukemia. 2019 Dec;33(12):2830-2841. doi: 10.1038/s41375-019-0505-x. Epub 2019 Jun 10. Leukemia. 2019. PMID: 31182782
Reptin drives tumour progression and resistance to chemotherapy in nonsmall cell lung cancer.
Mikesch JH, Schwammbach D, Hartmann W, Schmidt LH, Schliemann C, Angenendt L, Wiewrodt R, Marra A, Thoennissen NH, Wardelmann E, Köhler G, Lenz G, Müller-Tidow C, Berdel WE, Arteaga MF. Mikesch JH, et al. Among authors: arteaga mf. Eur Respir J. 2018 Jul 11;52(1):1701637. doi: 10.1183/13993003.01637-2017. Print 2018 Jul. Eur Respir J. 2018. PMID: 29853494 Free article.
MYST2 acetyltransferase expression and Histone H4 Lysine acetylation are suppressed in AML.
Sauer T, Arteaga MF, Isken F, Rohde C, Hebestreit K, Mikesch JH, Stelljes M, Cui C, Zhou F, Göllner S, Bäumer N, Köhler G, Krug U, Thiede C, Ehninger G, Edemir B, Schlenke P, Berdel WE, Dugas M, Müller-Tidow C. Sauer T, et al. Among authors: arteaga mf. Exp Hematol. 2015 Sep;43(9):794-802.e4. doi: 10.1016/j.exphem.2015.05.010. Epub 2015 Jun 11. Exp Hematol. 2015. PMID: 26072331 Free article.
C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia.
Yusenko MV, Trentmann A, Casolari DA, Abdel Ghani L, Lenz M, Horn M, Dörner W, Klempnauer S, Mootz HD, Arteaga MF, Mikesch JH, D'Andrea RJ, Gonda TJ, Müller-Tidow C, Schmidt TJ, Klempnauer KH. Yusenko MV, et al. Among authors: arteaga mf. Oncogene. 2021 Jul;40(29):4746-4758. doi: 10.1038/s41388-021-01800-x. Epub 2021 May 6. Oncogene. 2021. PMID: 33958723 Free PMC article.
Focal adhesion kinase confers pro-migratory and antiapoptotic properties and is a potential therapeutic target in Ewing sarcoma.
Steinestel K, Trautmann M, Jansen EP, Dirksen U, Rehkämper J, Mikesch JH, Gerke JS, Orth MF, Sannino G, Arteaga MF, Rossig C, Wardelmann E, Grünewald TGP, Hartmann W. Steinestel K, et al. Among authors: arteaga mf. Mol Oncol. 2020 Feb;14(2):248-260. doi: 10.1002/1878-0261.12610. Epub 2019 Dec 21. Mol Oncol. 2020. PMID: 31811703 Free PMC article.
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