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The Novel Arylamidine T-2307 Selectively Disrupts Yeast Mitochondrial Function by Inhibiting Respiratory Chain Complexes.
Yamashita K, Miyazaki T, Fukuda Y, Mitsuyama J, Saijo T, Shimamura S, Yamamoto K, Imamura Y, Izumikawa K, Yanagihara K, Kohno S, Mukae H. Yamashita K, et al. Among authors: mitsuyama j. Antimicrob Agents Chemother. 2019 Jul 25;63(8):e00374-19. doi: 10.1128/AAC.00374-19. Print 2019 Aug. Antimicrob Agents Chemother. 2019. PMID: 31182539 Free PMC article.
The novel arylamidine T-2307 maintains in vitro and in vivo activity against echinocandin-resistant Candida albicans.
Wiederhold NP, Najvar LK, Fothergill AW, Bocanegra R, Olivo M, McCarthy DI, Kirkpatrick WR, Fukuda Y, Mitsuyama J, Patterson TF. Wiederhold NP, et al. Among authors: mitsuyama j. Antimicrob Agents Chemother. 2015 Feb;59(2):1341-3. doi: 10.1128/AAC.04228-14. Epub 2014 Dec 1. Antimicrob Agents Chemother. 2015. PMID: 25451054 Free PMC article.
In vitro and in vivo antifungal activities of T-2307, a novel arylamidine, against Cryptococcus gattii: an emerging fungal pathogen.
Nishikawa H, Fukuda Y, Mitsuyama J, Tashiro M, Tanaka A, Takazono T, Saijo T, Yamamoto K, Nakamura S, Imamura Y, Miyazaki T, Kakeya H, Yamamoto Y, Yanagihara K, Mukae H, Kohno S, Izumikawa K. Nishikawa H, et al. Among authors: mitsuyama j. J Antimicrob Chemother. 2017 Jun 1;72(6):1709-1713. doi: 10.1093/jac/dkx020. J Antimicrob Chemother. 2017. PMID: 28201509 Free PMC article.
Antifungal susceptibility trend and analysis of resistance mechanism for Candida species isolated from bloodstream at a Japanese university hospital.
Sakagami T, Kawano T, Yamashita K, Yamada E, Fujino N, Kaeriyama M, Fukuda Y, Nomura N, Mitsuyama J, Suematsu H, Watanabe H, Asai N, Koizumi Y, Yamagishi Y, Mikamo H. Sakagami T, et al. Among authors: mitsuyama j. J Infect Chemother. 2019 Jan;25(1):34-40. doi: 10.1016/j.jiac.2018.10.007. Epub 2018 Nov 3. J Infect Chemother. 2019. PMID: 30401513
In vitro and in vivo antifungal activities of T-2307, a novel arylamidine.
Mitsuyama J, Nomura N, Hashimoto K, Yamada E, Nishikawa H, Kaeriyama M, Kimura A, Todo Y, Narita H. Mitsuyama J, et al. Antimicrob Agents Chemother. 2008 Apr;52(4):1318-24. doi: 10.1128/AAC.01159-07. Epub 2008 Jan 28. Antimicrob Agents Chemother. 2008. PMID: 18227186 Free PMC article.
57 results