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The Complexity of PRC2 Subcomplexes.
van Mierlo G, Veenstra GJC, Vermeulen M, Marks H. van Mierlo G, et al. Among authors: vermeulen m. Trends Cell Biol. 2019 Aug;29(8):660-671. doi: 10.1016/j.tcb.2019.05.004. Epub 2019 Jun 6. Trends Cell Biol. 2019. PMID: 31178244 Free article. Review.
Active DNA demethylation at enhancers during the vertebrate phylotypic period.
Bogdanović O, Smits AH, de la Calle Mustienes E, Tena JJ, Ford E, Williams R, Senanayake U, Schultz MD, Hontelez S, van Kruijsbergen I, Rayon T, Gnerlich F, Carell T, Veenstra GJ, Manzanares M, Sauka-Spengler T, Ecker JR, Vermeulen M, Gómez-Skarmeta JL, Lister R. Bogdanović O, et al. Among authors: vermeulen m. Nat Genet. 2016 Apr;48(4):417-26. doi: 10.1038/ng.3522. Epub 2016 Feb 29. Nat Genet. 2016. PMID: 26928226 Free PMC article.
ZMYND8 Co-localizes with NuRD on Target Genes and Regulates Poly(ADP-Ribose)-Dependent Recruitment of GATAD2A/NuRD to Sites of DNA Damage.
Spruijt CG, Luijsterburg MS, Menafra R, Lindeboom RG, Jansen PW, Edupuganti RR, Baltissen MP, Wiegant WW, Voelker-Albert MC, Matarese F, Mensinga A, Poser I, Vos HR, Stunnenberg HG, van Attikum H, Vermeulen M. Spruijt CG, et al. Among authors: vermeulen m. Cell Rep. 2016 Oct 11;17(3):783-798. doi: 10.1016/j.celrep.2016.09.037. Cell Rep. 2016. PMID: 27732854 Free article.
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma.
Brien GL, Remillard D, Shi J, Hemming ML, Chabon J, Wynne K, Dillon ET, Cagney G, Van Mierlo G, Baltissen MP, Vermeulen M, Qi J, Fröhling S, Gray NS, Bradner JE, Vakoc CR, Armstrong SA. Brien GL, et al. Among authors: vermeulen m. Elife. 2018 Nov 15;7:e41305. doi: 10.7554/eLife.41305. Elife. 2018. PMID: 30431433 Free PMC article.
Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency.
van Mierlo G, Dirks RAM, De Clerck L, Brinkman AB, Huth M, Kloet SL, Saksouk N, Kroeze LI, Willems S, Farlik M, Bock C, Jansen JH, Deforce D, Vermeulen M, Déjardin J, Dhaenens M, Marks H. van Mierlo G, et al. Among authors: vermeulen m. Cell Stem Cell. 2019 Jan 3;24(1):123-137.e8. doi: 10.1016/j.stem.2018.10.017. Epub 2018 Nov 21. Cell Stem Cell. 2019. PMID: 30472157 Free article.
EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer.
Wassef M, Luscan A, Aflaki S, Zielinski D, Jansen PWTC, Baymaz HI, Battistella A, Kersouani C, Servant N, Wallace MR, Romero P, Kosmider O, Just PA, Hivelin M, Jacques S, Vincent-Salomon A, Vermeulen M, Vidaud M, Pasmant E, Margueron R. Wassef M, et al. Among authors: vermeulen m. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6075-6080. doi: 10.1073/pnas.1814634116. Epub 2019 Mar 13. Proc Natl Acad Sci U S A. 2019. PMID: 30867289 Free PMC article.
1,035 results