Barrile R - Search Results

1

Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications.

Vatine GD, Barrile R, Workman MJ, Sances S, Barriga BK, Rahnama M, Barthakur S, Kasendra M, Lucchesi C, Kerns J, Wen N, Spivia WR, Chen Z, Van Eyk J, Svendsen CN. Vatine GD, et al. Among authors: barrile r. Cell Stem Cell. 2019 Jun 6;24(6):995-1005.e6. doi: 10.1016/j.stem.2019.05.011. Cell Stem Cell. 2019. PMID: 31173718 Free article.

2

A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it.

Varone A, Nguyen JK, Leng L, Barrile R, Sliz J, Lucchesi C, Wen N, Gravanis A, Hamilton GA, Karalis K, Hinojosa CD. Varone A, et al. Among authors: barrile r. Biomaterials. 2021 Aug;275:120957. doi: 10.1016/j.biomaterials.2021.120957. Epub 2021 Jun 6. Biomaterials. 2021. PMID: 34130145

3

Clostridium difficile toxins facilitate bacterial colonization by modulating the fence and gate function of colonic epithelium.

Kasendra M, Barrile R, Leuzzi R, Soriani M. Kasendra M, et al. Among authors: barrile r. J Infect Dis. 2014 Apr 1;209(7):1095-104. doi: 10.1093/infdis/jit617. Epub 2013 Nov 22. J Infect Dis. 2014. PMID: 24273043

4

Neisseria meningitidis subverts the polarized organization and intracellular trafficking of host cells to cross the epithelial barrier.

Barrile R, Kasendra M, Rossi-Paccani S, Merola M, Pizza M, Baldari C, Soriani M, Aricò B. Barrile R, et al. Cell Microbiol. 2015 Sep;17(9):1365-75. doi: 10.1111/cmi.12439. Epub 2015 Apr 23. Cell Microbiol. 2015. PMID: 25801707

5

Stem cell-based Lung-on-Chips: The best of both worlds?

Nawroth JC, Barrile R, Conegliano D, van Riet S, Hiemstra PS, Villenave R. Nawroth JC, et al. Among authors: barrile r. Adv Drug Deliv Rev. 2019 Feb 1;140:12-32. doi: 10.1016/j.addr.2018.07.005. Epub 2018 Jul 25. Adv Drug Deliv Rev. 2019. PMID: 30009883 Free PMC article. Review.

6

Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics.

Jain A, Barrile R, van der Meer AD, Mammoto A, Mammoto T, De Ceunynck K, Aisiku O, Otieno MA, Louden CS, Hamilton GA, Flaumenhaft R, Ingber DE. Jain A, et al. Among authors: barrile r. Clin Pharmacol Ther. 2018 Feb;103(2):332-340. doi: 10.1002/cpt.742. Epub 2017 Jul 14. Clin Pharmacol Ther. 2018. PMID: 28516446 Free PMC article.

7

Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium.

Jain A, van der Meer AD, Papa AL, Barrile R, Lai A, Schlechter BL, Otieno MA, Louden CS, Hamilton GA, Michelson AD, Frelinger AL 3rd, Ingber DE. Jain A, et al. Among authors: barrile r. Biomed Microdevices. 2016 Aug;18(4):73. doi: 10.1007/s10544-016-0095-6. Biomed Microdevices. 2016. PMID: 27464497 Free PMC article.

8

Reproducing human and cross-species drug toxicities using a Liver-Chip.

Jang KJ, Otieno MA, Ronxhi J, Lim HK, Ewart L, Kodella KR, Petropolis DB, Kulkarni G, Rubins JE, Conegliano D, Nawroth J, Simic D, Lam W, Singer M, Barale E, Singh B, Sonee M, Streeter AJ, Manthey C, Jones B, Srivastava A, Andersson LC, Williams D, Park H, Barrile R, Sliz J, Herland A, Haney S, Karalis K, Ingber DE, Hamilton GA. Jang KJ, et al. Among authors: barrile r. Sci Transl Med. 2019 Nov 6;11(517):eaax5516. doi: 10.1126/scitranslmed.aax5516. Sci Transl Med. 2019. PMID: 31694927

9

Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems.

Barrile R, van der Meer AD, Park H, Fraser JP, Simic D, Teng F, Conegliano D, Nguyen J, Jain A, Zhou M, Karalis K, Ingber DE, Hamilton GA, Otieno MA. Barrile R, et al. Clin Pharmacol Ther. 2018 Dec;104(6):1240-1248. doi: 10.1002/cpt.1054. Epub 2018 Apr 30. Clin Pharmacol Ther. 2018. PMID: 29484632

10

Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies.

Kerns SJ, Belgur C, Petropolis D, Kanellias M, Barrile R, Sam J, Weinzierl T, Fauti T, Freimoser-Grundschober A, Eckmann J, Hage C, Geiger M, Ng PR, Tien-Street W, Manatakis DV, Micallef V, Gerard R, Bscheider M, Breous-Nystrom E, Schneider A, Giusti AM, Bertinetti-Lapatki C, Grant HS, Roth AB, Hamilton GA, Singer T, Karalis K, Moisan A, Bruenker P, Klein C, Bacac M, Gjorevski N, Cabon L. Kerns SJ, et al. Among authors: barrile r. Elife. 2021 Aug 11;10:e67106. doi: 10.7554/eLife.67106. Elife. 2021. PMID: 34378534 Free PMC article.

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