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Page 1
Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals.
Mandaviya PR, Joehanes R, Brody J, Castillo-Fernandez JE, Dekkers KF, Do AN, Graff M, Hänninen IK, Tanaka T, de Jonge EAL, Kiefte-de Jong JC, Absher DM, Aslibekyan S, de Rijke YB, Fornage M, Hernandez DG, Hurme MA, Ikram MA, Jacques PF, Justice AE, Kiel DP, Lemaitre RN, Mendelson MM, Mikkilä V, Moore AZ, Pallister T, Raitakari OT, Schalkwijk CG, Sha J, Slagboom EPE, Smith CE, Stehouwer CDA, Tsai PC, Uitterlinden AG, van der Kallen CJH, van Heemst D, Arnett DK, Bandinelli S, Bell JT, Heijmans BT, Lehtimäki T, Levy D, North KE, Sotoodehnia N, van Greevenbroek MMJ, van Meurs JBJ, Heil SG. Mandaviya PR, et al. Among authors: van heemst d, van meurs jbj, van greevenbroek mmj, van der kallen cjh. Am J Clin Nutr. 2019 Aug 1;110(2):437-450. doi: 10.1093/ajcn/nqz031. Am J Clin Nutr. 2019. PMID: 31165884 Free PMC article.
Reduced insulin/IGF-1 signalling and human longevity.
van Heemst D, Beekman M, Mooijaart SP, Heijmans BT, Brandt BW, Zwaan BJ, Slagboom PE, Westendorp RG. van Heemst D, et al. Aging Cell. 2005 Apr;4(2):79-85. doi: 10.1111/j.1474-9728.2005.00148.x. Aging Cell. 2005. PMID: 15771611 Free article.
Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study.
Westendorp RG, van Heemst D, Rozing MP, Frölich M, Mooijaart SP, Blauw GJ, Beekman M, Heijmans BT, de Craen AJ, Slagboom PE; Leiden Longevity Study Group. Westendorp RG, et al. Among authors: van heemst d. J Am Geriatr Soc. 2009 Sep;57(9):1634-7. doi: 10.1111/j.1532-5415.2009.02381.x. Epub 2009 Jul 17. J Am Geriatr Soc. 2009. PMID: 19682117
Low serum free triiodothyronine levels mark familial longevity: the Leiden Longevity Study.
Rozing MP, Westendorp RG, de Craen AJ, Frölich M, Heijmans BT, Beekman M, Wijsman C, Mooijaart SP, Blauw GJ, Slagboom PE, van Heemst D; Leiden Longevity Study (LLS) Group. Rozing MP, et al. Among authors: van heemst d. J Gerontol A Biol Sci Med Sci. 2010 Apr;65(4):365-8. doi: 10.1093/gerona/glp200. Epub 2009 Dec 16. J Gerontol A Biol Sci Med Sci. 2010. PMID: 20018826
Human insulin/IGF-1 and familial longevity at middle age.
Rozing MP, Westendorp RG, Frölich M, de Craen AJ, Beekman M, Heijmans BT, Mooijaart SP, Blauw GJ, Slagboom PE, van Heemst D; Leiden Longevity Study (LLS) Group. Rozing MP, et al. Among authors: van heemst d. Aging (Albany NY). 2009 Jul 24;1(8):714-22. doi: 10.18632/aging.100071. Aging (Albany NY). 2009. PMID: 20157552 Free PMC article.
Favorable glucose tolerance and lower prevalence of metabolic syndrome in offspring without diabetes mellitus of nonagenarian siblings: the Leiden longevity study.
Rozing MP, Westendorp RG, de Craen AJ, Frölich M, de Goeij MC, Heijmans BT, Beekman M, Wijsman CA, Mooijaart SP, Blauw GJ, Slagboom PE, van Heemst D; Leiden Longevity Study Group. Rozing MP, et al. Among authors: van heemst d. J Am Geriatr Soc. 2010 Mar;58(3):564-9. doi: 10.1111/j.1532-5415.2010.02725.x. J Am Geriatr Soc. 2010. PMID: 20398121
Lipid metabolism in long-lived families: the Leiden Longevity Study.
Vaarhorst AA, Beekman M, Suchiman EH, van Heemst D, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE, Heijmans BT; Leiden Longevity Study (LLS) Group. Vaarhorst AA, et al. Among authors: van heemst d. Age (Dordr). 2011 Jun;33(2):219-27. doi: 10.1007/s11357-010-9172-6. Epub 2010 Sep 3. Age (Dordr). 2011. PMID: 20811950 Free PMC article.
C-reactive protein and glucose regulation in familial longevity.
Rozing MP, Mooijaart SP, Beekman M, Wijsman CA, Maier AB, Bartke A, Westendorp RG, Slagboom EP, van Heemst D. Rozing MP, et al. Among authors: van heemst d. Age (Dordr). 2011 Dec;33(4):623-30. doi: 10.1007/s11357-011-9206-8. Epub 2011 Jan 19. Age (Dordr). 2011. PMID: 21246407 Free PMC article.
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.
Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, Rivadeneira F, de Geus EJ, Perola M, van der Ouderaa FJ, Gunn DA, Boomsma DI, Uitterlinden AG, Christensen K, van Duijn CM, Heijmans BT, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE. Deelen J, et al. Among authors: van den akker eb, van duijn cm, van heemst d, van der ouderaa fj, van der breggen r. Aging Cell. 2011 Aug;10(4):686-98. doi: 10.1111/j.1474-9726.2011.00705.x. Epub 2011 May 6. Aging Cell. 2011. PMID: 21418511 Free PMC article.
Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways.
Deelen J, Uh HW, Monajemi R, van Heemst D, Thijssen PE, Böhringer S, van den Akker EB, de Craen AJ, Rivadeneira F, Uitterlinden AG, Westendorp RG, Goeman JJ, Slagboom PE, Houwing-Duistermaat JJ, Beekman M. Deelen J, et al. Among authors: van den akker eb, van heemst d. Age (Dordr). 2013 Feb;35(1):235-49. doi: 10.1007/s11357-011-9340-3. Epub 2011 Nov 24. Age (Dordr). 2013. PMID: 22113349 Free PMC article.
308 results