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Anti-Alzheimer's multitarget-directed ligands with serotonin 5-HT6 antagonist, butyrylcholinesterase inhibitory, and antioxidant activity.
Marcinkowska M, Bucki A, Panek D, Siwek A, Fajkis N, Bednarski M, Zygmunt M, Godyń J, Del Rio Valdivieso A, Kotańska M, Kołaczkowski M, Więckowska A. Marcinkowska M, et al. Among authors: kotanska m. Arch Pharm (Weinheim). 2019 Jul;352(7):e1900041. doi: 10.1002/ardp.201900041. Epub 2019 Jun 4. Arch Pharm (Weinheim). 2019. PMID: 31162703
Chemically Homogenous Compounds with Antagonistic Properties at All α1-Adrenoceptor Subtypes but not β1-Adrenoceptor Attenuate Adrenaline-Induced Arrhythmia in Rats.
Pytka K, Lustyk K, Żmudzka E, Kotańska M, Siwek A, Zygmunt M, Dziedziczak A, Śniecikowska J, Olczyk A, Gałuszka A, Śmieja J, Waszkielewicz AM, Marona H, Filipek B, Sapa J, Mogilski S. Pytka K, et al. Among authors: kotanska m. Front Pharmacol. 2016 Aug 3;7:229. doi: 10.3389/fphar.2016.00229. eCollection 2016. Front Pharmacol. 2016. PMID: 27536240 Free PMC article.
Arylsulfonamide derivatives of (aryloxy)ethyl pyrrolidines and piperidines as α1-adrenergic receptor antagonist with uro-selective activity.
Rak A, Canale V, Marciniec K, Żmudzki P, Kotańska M, Knutelska J, Siwek A, Stachowicz G, Bednarski M, Nowiński L, Zygmunt M, Zajdel P, Sapa J. Rak A, et al. Among authors: kotanska m. Bioorg Med Chem. 2016 Nov 1;24(21):5582-5591. doi: 10.1016/j.bmc.2016.09.017. Epub 2016 Sep 10. Bioorg Med Chem. 2016. PMID: 27658792
Synthesis and biological evaluation of N-arylpiperazine derivatives of 4,4-dimethylisoquinoline-1,3(2H,4H)-dione as potential antiplatelet agents.
Marcinkowska M, Kotańska M, Zagórska A, Śniecikowska J, Kubacka M, Siwek A, Bucki A, Pawłowski M, Bednarski M, Sapa J, Starek M, Dąbrowska M, Kołaczkowski M. Marcinkowska M, et al. Among authors: kotanska m. J Enzyme Inhib Med Chem. 2018 Dec;33(1):536-545. doi: 10.1080/14756366.2018.1437155. J Enzyme Inhib Med Chem. 2018. PMID: 29482394 Free PMC article.
Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H3R ligands.
Szczepańska K, Karcz T, Mogilski S, Siwek A, Kuder KJ, Latacz G, Kubacka M, Hagenow S, Lubelska A, Olejarz A, Kotańska M, Sadek B, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: kotanska m. Eur J Med Chem. 2018 May 25;152:223-234. doi: 10.1016/j.ejmech.2018.04.043. Epub 2018 Apr 25. Eur J Med Chem. 2018. PMID: 29723785
61 results