Holst J - Search Results

1

Wahi K, Holst J. Wahi K, et al. Among authors: holst j. Expert Opin Ther Targets. 2019 Jul;23(7):555-558. doi: 10.1080/14728222.2019.1627328. Epub 2019 Jun 4. Expert Opin Ther Targets. 2019. PMID: 31159623 No abstract available.

2

Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development.

Wang Q, Hardie RA, Hoy AJ, van Geldermalsen M, Gao D, Fazli L, Sadowski MC, Balaban S, Schreuder M, Nagarajah R, Wong JJ, Metierre C, Pinello N, Otte NJ, Lehman ML, Gleave M, Nelson CC, Bailey CG, Ritchie W, Rasko JE, Holst J. Wang Q, et al. Among authors: holst j. J Pathol. 2015 Jul;236(3):278-89. doi: 10.1002/path.4518. Epub 2015 Apr 7. J Pathol. 2015. PMID: 25693838 Free PMC article.

3

ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer.

van Geldermalsen M, Wang Q, Nagarajah R, Marshall AD, Thoeng A, Gao D, Ritchie W, Feng Y, Bailey CG, Deng N, Harvey K, Beith JM, Selinger CI, O'Toole SA, Rasko JE, Holst J. van Geldermalsen M, et al. Among authors: holst j. Oncogene. 2016 Jun 16;35(24):3201-8. doi: 10.1038/onc.2015.381. Epub 2015 Oct 12. Oncogene. 2016. PMID: 26455325 Free PMC article.

4

Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells.

Bröer A, Gauthier-Coles G, Rahimi F, van Geldermalsen M, Dorsch D, Wegener A, Holst J, Bröer S. Bröer A, et al. Among authors: holst j. J Biol Chem. 2019 Mar 15;294(11):4012-4026. doi: 10.1074/jbc.RA118.006378. Epub 2019 Jan 11. J Biol Chem. 2019. PMID: 30635397 Free PMC article.

5

Synthesis of bilocularin A carbamate derivatives and their evaluation as leucine transport inhibitors in prostate cancer cells.

Huxley C, Wibowo M, Lum KY, Gordon S, D'Hyon S, Guan H, Wang X, Chen Y, Si M, Wang M, White JM, Wahi K, Wang Q, Holst J, Davis RA. Huxley C, et al. Among authors: holst j. Phytochemistry. 2020 Nov;179:112478. doi: 10.1016/j.phytochem.2020.112478. Epub 2020 Aug 14. Phytochemistry. 2020. PMID: 32805621

6

Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth.

Wang Q, Guan YF, Hancock SE, Wahi K, van Geldermalsen M, Zhang BK, Pang A, Nagarajah R, Mak B, Freidman N, Horvath LG, Turner N, Holst J. Wang Q, et al. Among authors: holst j. J Pathol. 2021 Jun;254(2):135-146. doi: 10.1002/path.5665. Epub 2021 Apr 21. J Pathol. 2021. PMID: 33768538

7

Zwitterionic Amino Acid-Derived Polyacrylates as Smart Materials Exhibiting Cellular Specificity and Therapeutic Activity.

Leiske MN, Mazrad ZAI, Zelcak A, Wahi K, Davis TP, McCarroll JA, Holst J, Kempe K. Leiske MN, et al. Among authors: holst j. Biomacromolecules. 2022 Jun 13;23(6):2374-2387. doi: 10.1021/acs.biomac.2c00143. Epub 2022 May 4. Biomacromolecules. 2022. PMID: 35508075

8

Glutamine addiction promotes glucose oxidation in triple-negative breast cancer.

Quek LE, van Geldermalsen M, Guan YF, Wahi K, Mayoh C, Balaban S, Pang A, Wang Q, Cowley MJ, Brown KK, Turner N, Hoy AJ, Holst J. Quek LE, et al. Among authors: holst j. Oncogene. 2022 Aug;41(34):4066-4078. doi: 10.1038/s41388-022-02408-5. Epub 2022 Jul 18. Oncogene. 2022. PMID: 35851845 Free PMC article.

9

Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening.

Colas C, Grewer C, Otte NJ, Gameiro A, Albers T, Singh K, Shere H, Bonomi M, Holst J, Schlessinger A. Colas C, et al. Among authors: holst j. PLoS Comput Biol. 2015 Oct 7;11(10):e1004477. doi: 10.1371/journal.pcbi.1004477. eCollection 2015 Oct. PLoS Comput Biol. 2015. PMID: 26444490 Free PMC article.

10

LAT1 is a putative therapeutic target in endometrioid endometrial carcinoma.

Marshall AD, van Geldermalsen M, Otte NJ, Anderson LA, Lum T, Vellozzi MA, Zhang BK, Thoeng A, Wang Q, Rasko JE, Holst J. Marshall AD, et al. Among authors: holst j. Int J Cancer. 2016 Dec 1;139(11):2529-39. doi: 10.1002/ijc.30371. Epub 2016 Aug 16. Int J Cancer. 2016. PMID: 27486861 Free article.

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