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The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation.
Cell Chem Biol. 2019 Aug 15;26(8):1133-1142.e4. doi: 10.1016/j.chembiol.2019.04.011. Epub 2019 May 30.
Cell Chem Biol. 2019.
PMID: 31155509
Free PMC article.
Stereoselective Synthesis, Docking, and Biological Evaluation of Difluoroindanediol-Based MenE Inhibitors as Antibiotics.
Evans CE, Matarlo JS, Tonge PJ, Tan DS.
Evans CE, et al. Among authors: matarlo js.
Org Lett. 2016 Dec 16;18(24):6384-6387. doi: 10.1021/acs.orglett.6b03272. Epub 2016 Dec 1.
Org Lett. 2016.
PMID: 27978658
Free PMC article.
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Mechanism of MenE inhibition by acyl-adenylate analogues and discovery of novel antibacterial agents.
Matarlo JS, Evans CE, Sharma I, Lavaud LJ, Ngo SC, Shek R, Rajashankar KR, French JB, Tan DS, Tonge PJ.
Matarlo JS, et al.
Biochemistry. 2015 Oct 27;54(42):6514-6524. doi: 10.1021/acs.biochem.5b00966. Epub 2015 Oct 15.
Biochemistry. 2015.
PMID: 26394156
Free PMC article.
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Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE.
Evans CE, Si Y, Matarlo JS, Yin Y, French JB, Tonge PJ, Tan DS.
Evans CE, et al. Among authors: matarlo js.
Biochemistry. 2019 Apr 9;58(14):1918-1930. doi: 10.1021/acs.biochem.9b00003. Epub 2019 Mar 26.
Biochemistry. 2019.
PMID: 30912442
Free PMC article.
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A Methyl 4-Oxo-4-phenylbut-2-enoate with in Vivo Activity against MRSA that Inhibits MenB in the Bacterial Menaquinone Biosynthesis Pathway.
Matarlo JS, Lu Y, Daryaee F, Daryaee T, Ruzsicska B, Walker SG, Tonge PJ.
Matarlo JS, et al.
ACS Infect Dis. 2016 May 13;2(5):329-340. doi: 10.1021/acsinfecdis.6b00023. Epub 2016 Mar 7.
ACS Infect Dis. 2016.
PMID: 27294200
Free PMC article.
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Knockdown of miR-23, miR-27, and miR-24 Alters Fetal Liver Development and Blocks Fibrosis in Mice.
Rogler CE, Matarlo JS, Kosmyna B, Fulop D, Rogler LE.
Rogler CE, et al. Among authors: matarlo js.
Gene Expr. 2017 Feb 10;17(2):99-114. doi: 10.3727/105221616X693891. Epub 2016 Nov 23.
Gene Expr. 2017.
PMID: 27938504
Free PMC article.
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