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The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress.
Sagliocchi S, Cicatiello AG, Di Cicco E, Ambrosio R, Miro C, Di Girolamo D, Nappi A, Mancino G, De Stefano MA, Luongo C, Raia M, Ogawa-Wong AN, Zavacki AM, Paladino S, Salvatore D, Dentice M. Sagliocchi S, et al. Among authors: salvatore d. Redox Biol. 2019 Jun;24:101228. doi: 10.1016/j.redox.2019.101228. Epub 2019 May 22. Redox Biol. 2019. PMID: 31153038 Free PMC article.
Missense mutation in the transcription factor NKX2-5: a novel molecular event in the pathogenesis of thyroid dysgenesis.
Dentice M, Cordeddu V, Rosica A, Ferrara AM, Santarpia L, Salvatore D, Chiovato L, Perri A, Moschini L, Fazzini C, Olivieri A, Costa P, Stoppioni V, Baserga M, De Felice M, Sorcini M, Fenzi G, Di Lauro R, Tartaglia M, Macchia PE. Dentice M, et al. Among authors: salvatore d. J Clin Endocrinol Metab. 2006 Apr;91(4):1428-33. doi: 10.1210/jc.2005-1350. Epub 2006 Jan 17. J Clin Endocrinol Metab. 2006. PMID: 16418214
Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.
Dentice M, Luongo C, Huang S, Ambrosio R, Elefante A, Mirebeau-Prunier D, Zavacki AM, Fenzi G, Grachtchouk M, Hutchin M, Dlugosz AA, Bianco AC, Missero C, Larsen PR, Salvatore D. Dentice M, et al. Among authors: salvatore d. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14466-71. doi: 10.1073/pnas.0706754104. Epub 2007 Aug 24. Proc Natl Acad Sci U S A. 2007. PMID: 17720805 Free PMC article.
Role of type 3 deiodinase in cancer.
Dentice M, Ambrosio R, Salvatore D. Dentice M, et al. Among authors: salvatore d. Expert Opin Ther Targets. 2009 Nov;13(11):1363-73. doi: 10.1517/14728220903339122. Expert Opin Ther Targets. 2009. PMID: 19764892 Review.
Type 2 iodothyronine deiodinase levels are higher in slow-twitch than fast-twitch mouse skeletal muscle and are increased in hypothyroidism.
Marsili A, Ramadan W, Harney JW, Mulcahey M, Castroneves LA, Goemann IM, Wajner SM, Huang SA, Zavacki AM, Maia AL, Dentice M, Salvatore D, Silva JE, Larsen PR. Marsili A, et al. Among authors: salvatore d. Endocrinology. 2010 Dec;151(12):5952-60. doi: 10.1210/en.2010-0631. Epub 2010 Sep 29. Endocrinology. 2010. PMID: 20881246 Free PMC article.
559 results