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BLT1 mediates commensal bacteria-dependent innate immune signals to enhance antigen-specific intestinal IgA responses.
Nagatake T, Hirata SI, Koga T, Kuroda E, Kobari S, Suzuki H, Hosomi K, Matsumoto N, Yanrismet Y, Shimojou M, Morimoto S, Sasaki F, Ishii KJ, Yokomizo T, Kunisawa J. Nagatake T, et al. Among authors: ishii kj. Mucosal Immunol. 2019 Sep;12(5):1082-1091. doi: 10.1038/s41385-019-0175-z. Epub 2019 May 29. Mucosal Immunol. 2019. PMID: 31142830 Free article.
Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist.
Kobiyama K, Aoshi T, Narita H, Kuroda E, Hayashi M, Tetsutani K, Koyama S, Mochizuki S, Sakurai K, Katakai Y, Yasutomi Y, Saijo S, Iwakura Y, Akira S, Coban C, Ishii KJ. Kobiyama K, et al. Among authors: ishii kj. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3086-91. doi: 10.1073/pnas.1319268111. Epub 2014 Feb 10. Proc Natl Acad Sci U S A. 2014. PMID: 24516163 Free PMC article.
Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome.
Takemura N, Kawasaki T, Kunisawa J, Sato S, Lamichhane A, Kobiyama K, Aoshi T, Ito J, Mizuguchi K, Karuppuchamy T, Matsunaga K, Miyatake S, Mori N, Tsujimura T, Satoh T, Kumagai Y, Kawai T, Standley DM, Ishii KJ, Kiyono H, Akira S, Uematsu S. Takemura N, et al. Among authors: ishii kj. Nat Commun. 2014 Mar 18;5:3492. doi: 10.1038/ncomms4492. Nat Commun. 2014. PMID: 24637670 Free PMC article.
Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.
Onishi M, Ozasa K, Kobiyama K, Ohata K, Kitano M, Taniguchi K, Homma T, Kobayashi M, Sato A, Katakai Y, Yasutomi Y, Wijaya E, Igarashi Y, Nakatsu N, Ise W, Inoue T, Yamada H, Vandenbon A, Standley DM, Kurosaki T, Coban C, Aoshi T, Kuroda E, Ishii KJ. Onishi M, et al. Among authors: ishii kj. J Immunol. 2015 Mar 15;194(6):2673-82. doi: 10.4049/jimmunol.1402027. Epub 2015 Feb 13. J Immunol. 2015. PMID: 25681338 Free PMC article.
270 results