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Prostaglandin E2 in a TLR3- and 7/8-agonist-based DC maturation cocktail generates mature, cytokine-producing, migratory DCs but impairs antigen cross-presentation to CD8+ T cells.
Gierlich P, Lex V, Technau A, Keupp A, Morper L, Glunz A, Sennholz H, Rachor J, Sauer S, Marcu A, Grigoleit GU, Wölfl M, Schlegel PG, Eyrich M. Gierlich P, et al. Among authors: keupp a. Cancer Immunol Immunother. 2020 Jun;69(6):1029-1042. doi: 10.1007/s00262-019-02470-1. Epub 2020 Feb 25. Cancer Immunol Immunother. 2020. PMID: 32100075 Free PMC article.
Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors.
Marcu A, Schlosser A, Keupp A, Trautwein N, Johann P, Wölfl M, Lager J, Monoranu CM, Walz JS, Henkel LM, Krauß J, Ebinger M, Schuhmann M, Thomale UW, Pietsch T, Klinker E, Schlegel PG, Oyen F, Reisner Y, Rammensee HG, Eyrich M. Marcu A, et al. Among authors: keupp a. J Immunother Cancer. 2021 Oct;9(10):e003404. doi: 10.1136/jitc-2021-003404. J Immunother Cancer. 2021. PMID: 34599019 Free PMC article.