Chan K - Search Results

1

Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi^®.

Taylor JG, Zipfel S, Ramey K, Vivian R, Schrier A, Karki KK, Katana A, Kato D, Kobayashi T, Martinez R, Sangi M, Siegel D, Tran CV, Yang ZY, Zablocki J, Yang CY, Wang Y, Wang K, Chan K, Barauskas O, Cheng G, Jin D, Schultz BE, Appleby T, Villaseñor AG, Link JO. Taylor JG, et al. Among authors: chan k. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2428-2436. doi: 10.1016/j.bmcl.2019.03.037. Epub 2019 Mar 26. Bioorg Med Chem Lett. 2019. PMID: 31133531

2

Direct binding of ledipasvir to HCV NS5A: mechanism of resistance to an HCV antiviral agent.

Kwon HJ, Xing W, Chan K, Niedziela-Majka A, Brendza KM, Kirschberg T, Kato D, Link JO, Cheng G, Liu X, Sakowicz R. Kwon HJ, et al. Among authors: chan k. PLoS One. 2015 Apr 9;10(4):e0122844. doi: 10.1371/journal.pone.0122844. eCollection 2015. PLoS One. 2015. PMID: 25856426 Free PMC article.

3

Selection of clinically relevant protease inhibitor-resistant viruses using the genotype 2a hepatitis C virus infection system.

Cheng G, Chan K, Yang H, Corsa A, Pokrovskii M, Paulson M, Bahador G, Zhong W, Delaney W 4th. Cheng G, et al. Among authors: chan k. Antimicrob Agents Chemother. 2011 May;55(5):2197-205. doi: 10.1128/AAC.01382-10. Epub 2011 Feb 28. Antimicrob Agents Chemother. 2011. PMID: 21357305 Free PMC article.

4

An adaptive mutation in NS2 is essential for efficient production of infectious 1b/2a chimeric hepatitis C virus in cell culture.

Chan K, Cheng G, Beran RK, Yang H, Appleby TC, Pokrovskii MV, Mo H, Zhong W, Delaney WE 4th. Chan K, et al. Virology. 2012 Jan 20;422(2):224-34. doi: 10.1016/j.virol.2011.10.022. Epub 2011 Nov 17. Virology. 2012. PMID: 22099378 Free article.

5

In vitro efficacy of approved and experimental antivirals against novel genotype 3 hepatitis C virus subgenomic replicons.

Yu M, Corsa AC, Xu S, Peng B, Gong R, Lee YJ, Chan K, Mo H, Delaney W 4th, Cheng G. Yu M, et al. Among authors: chan k. Antiviral Res. 2013 Nov;100(2):439-45. doi: 10.1016/j.antiviral.2013.08.018. Epub 2013 Sep 5. Antiviral Res. 2013. PMID: 24013001

6

Robust and persistent replication of the genotype 6a hepatitis C virus replicon in cell culture.

Yu M, Peng B, Chan K, Gong R, Yang H, Delaney W 4th, Cheng G. Yu M, et al. Among authors: chan k. Antimicrob Agents Chemother. 2014 May;58(5):2638-46. doi: 10.1128/AAC.01780-13. Epub 2014 Feb 18. Antimicrob Agents Chemother. 2014. PMID: 24550344 Free PMC article.

7

Development of robust hepatitis C virus genotype 4 subgenomic replicons.

Peng B, Yu M, Xu S, Lee YJ, Tian Y, Yang H, Chan K, Mo H, McHutchison J, Delaney W 4th, Cheng G. Peng B, et al. Among authors: chan k. Gastroenterology. 2013 Jan;144(1):59-61.e6. doi: 10.1053/j.gastro.2012.09.033. Epub 2012 Sep 20. Gastroenterology. 2013. PMID: 23000598

8

Development of a robust luciferase reporter 1b/2a hepatitis C virus (HCV) for characterization of early stage HCV life cycle inhibitors.

Chan K, Robinson M, Yang H, Cornew S, Delaney Iv WE. Chan K, et al. Antiviral Res. 2013 Apr;98(1):85-92. doi: 10.1016/j.antiviral.2013.01.005. Epub 2013 Feb 1. Antiviral Res. 2013. PMID: 23376631

9

Retrograde closure of post-infarct ventricular septal rupture to avoid moderator band entanglement.

Ho CB, Wong I, Chiang MCS, Chui ASF, Chan AKC, Wong CY, Chan KT, Lee MKY. Ho CB, et al. Among authors: chan kt. J Invasive Cardiol. 2024 May 24. doi: 10.25270/jic/24.00137. Online ahead of print. J Invasive Cardiol. 2024. PMID: 38814905

10

Serotype-Specific Regulation of Dengue Virus NS5 Protein Subcellular Localization.

Cheng CX, Tan MJA, Chan KWK, Choy MMJ, Roman N, Arnold DDR, Bifani AM, Kong SYZ, Bist P, Nath BK, Swarbrick CMD, Forwood JK, Vasudevan SG. Cheng CX, et al. Among authors: chan kwk. ACS Infect Dis. 2024 May 29. doi: 10.1021/acsinfecdis.4c00054. Online ahead of print. ACS Infect Dis. 2024. PMID: 38811007

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