Su Y - Search Results

1

SAR study of celastrol analogs targeting Nur77-mediated inflammatory pathway.

Chen Z, Zhang D, Yan S, Hu C, Huang Z, Li Z, Peng S, Li X, Zhu Y, Yu H, Lian B, Kang Q, Li M, Zeng Z, Zhang XK, Su Y. Chen Z, et al. Among authors: su y. Eur J Med Chem. 2019 Sep 1;177:171-187. doi: 10.1016/j.ejmech.2019.05.009. Epub 2019 May 12. Eur J Med Chem. 2019. PMID: 31132532

2

Recent Progress in the Design and Discovery of RXR Modulators Targeting Alternate Binding Sites of the Receptor.

Su Y, Zeng Z, Chen Z, Xu D, Zhang W, Zhang XK. Su Y, et al. Curr Top Med Chem. 2017;17(6):663-675. doi: 10.2174/1568026616666160617092241. Curr Top Med Chem. 2017. PMID: 27320331 Review.

3

Binding characterization, synthesis and biological evaluation of RXRα antagonists targeting the coactivator binding site.

Xu D, Guo S, Chen Z, Bao Y, Huang F, Xu D, Zhang X, Zeng Z, Zhou H, Zhang X, Su Y. Xu D, et al. Among authors: su y. Bioorg Med Chem Lett. 2016 Aug 15;26(16):3846-9. doi: 10.1016/j.bmcl.2016.07.027. Epub 2016 Jul 14. Bioorg Med Chem Lett. 2016. PMID: 27450787

4

AlCl₃·6H₂O-Catalyzed Friedel-Crafts Alkylation of Indoles by the para-Quinone Methide Moiety of Celastrol.

Zhu Y, Chen Z, Huang Z, Yan S, Li Z, Zhou H, Zhang X, Su Y, Zeng Z. Zhu Y, et al. Among authors: su y. Molecules. 2017 May 16;22(5):742. doi: 10.3390/molecules22050742. Molecules. 2017. PMID: 28509859 Free PMC article.

5

Design, synthesis and biological evaluation of tetrazole-containing RXRα ligands as anticancer agents.

Yan Z, Chong S, Lin H, Yang Q, Wang X, Zhang W, Zhang X, Zeng Z, Su Y. Yan Z, et al. Among authors: su y. Eur J Med Chem. 2019 Feb 15;164:562-575. doi: 10.1016/j.ejmech.2018.12.036. Epub 2018 Dec 19. Eur J Med Chem. 2019. PMID: 30634084

6

Optimization of novel oxidative DIMs as Nur77 modulators of the Nur77-Bcl-2 apoptotic pathway.

Tu X, Chen X, Zhang D, Gao M, Liang J, Bao G, Zhang J, Peng S, Zhang X, Zeng Z, Su Y. Tu X, et al. Among authors: su y. Eur J Med Chem. 2021 Feb 5;211:113020. doi: 10.1016/j.ejmech.2020.113020. Epub 2020 Nov 13. Eur J Med Chem. 2021. PMID: 33279290

7

Design, synthesis, and biological evaluation of novel sulindac derivatives as partial agonists of PPARγ with potential anti-diabetic efficacy.

Huang F, Zeng Z, Zhang W, Yan Z, Chen J, Yu L, Yang Q, Li Y, Yu H, Chen J, Wu C, Zhang XK, Su Y, Zhou H. Huang F, et al. Among authors: su y. Eur J Med Chem. 2021 Oct 15;222:113542. doi: 10.1016/j.ejmech.2021.113542. Epub 2021 May 24. Eur J Med Chem. 2021. PMID: 34118723

8

Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates.

Peng SZ, Chen XH, Chen SJ, Zhang J, Wang CY, Liu WR, Zhang D, Su Y, Zhang XK. Peng SZ, et al. Among authors: su y. Nat Commun. 2021 Oct 13;12(1):5989. doi: 10.1038/s41467-021-26295-8. Nat Commun. 2021. PMID: 34645818 Free PMC article.

9

Synthesis and SAR study of modulators inhibiting tRXRα-dependent AKT activation.

Wang ZG, Chen L, Chen J, Zheng JF, Gao W, Zeng Z, Zhou H, Zhang XK, Huang PQ, Su Y. Wang ZG, et al. Among authors: su y. Eur J Med Chem. 2013 Apr;62:632-48. doi: 10.1016/j.ejmech.2013.01.012. Epub 2013 Jan 18. Eur J Med Chem. 2013. PMID: 23434637 Free PMC article.

10

Targeting truncated RXRα for cancer therapy.

Zhang X, Zhou H, Su Y. Zhang X, et al. Among authors: su y. Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):49-59. doi: 10.1093/abbs/gmv104. Epub 2015 Oct 21. Acta Biochim Biophys Sin (Shanghai). 2016. PMID: 26494413 Free PMC article. Review.

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