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New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease.
Zueva I, Dias J, Lushchekina S, Semenov V, Mukhamedyarov M, Pashirova T, Babaev V, Nachon F, Petrova N, Nurullin L, Zakharova L, Ilyin V, Masson P, Petrov K. Zueva I, et al. Among authors: nachon f. Neuropharmacology. 2019 Sep 1;155:131-141. doi: 10.1016/j.neuropharm.2019.05.025. Epub 2019 May 25. Neuropharmacology. 2019. PMID: 31132435
Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography.
Colletier JP, Royant A, Specht A, Sanson B, Nachon F, Masson P, Zaccai G, Sussman JL, Goeldner M, Silman I, Bourgeois D, Weik M. Colletier JP, et al. Among authors: nachon f. Acta Crystallogr D Biol Crystallogr. 2007 Nov;63(Pt 11):1115-28. doi: 10.1107/S0907444907044472. Epub 2007 Oct 17. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 18007027
136 results