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Pharmacology and function of the orphan GPR139 G protein-coupled receptor.
Vedel L, Nøhr AC, Gloriam DE, Bräuner-Osborne H. Vedel L, et al. Among authors: nohr ac. Basic Clin Pharmacol Toxicol. 2020 Jun;126 Suppl 6(Suppl 6):35-46. doi: 10.1111/bcpt.13263. Epub 2019 Jun 27. Basic Clin Pharmacol Toxicol. 2020. PMID: 31132229 Free PMC article. Review.
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.
Nøhr AC, Shehata MA, Hauser AS, Isberg V, Mokrosinski J, Andersen KB, Farooqi IS, Pedersen DS, Gloriam DE, Bräuner-Osborne H. Nøhr AC, et al. Neurochem Int. 2017 Jan;102:105-113. doi: 10.1016/j.neuint.2016.11.012. Epub 2016 Dec 1. Neurochem Int. 2017. PMID: 27916541 Free PMC article.