Xu W - Search Results

1

An Oncolytic Adenovirus Targeting Transforming Growth Factor β Inhibits Protumorigenic Signals and Produces Immune Activation: A Novel Approach to Enhance Anti-PD-1 and Anti-CTLA-4 Therapy.

Yang Y, Xu W, Peng D, Wang H, Zhang X, Wang H, Xiao F, Zhu Y, Ji Y, Gulukota K, Helseth DL Jr, Mangold KA, Sullivan M, Kaul K, Wang E, Prabhakar BS, Li J, Wu X, Wang L, Seth P. Yang Y, et al. Among authors: xu w. Hum Gene Ther. 2019 Sep;30(9):1117-1132. doi: 10.1089/hum.2019.059. Epub 2019 Jul 1. Hum Gene Ther. 2019. PMID: 31126191 Free PMC article.

2

Ad5/48 hexon oncolytic virus expressing sTGFβRIIFc produces reduced hepatic and systemic toxicities and inhibits prostate cancer bone metastases.

Xu W, Zhang Z, Yang Y, Hu Z, Wang CH, Morgan M, Wu Y, Hutten R, Xiao X, Stock S, Guise T, Prabhakar BS, Brendler C, Seth P. Xu W, et al. Mol Ther. 2014 Aug;22(8):1504-1517. doi: 10.1038/mt.2014.80. Epub 2014 May 5. Mol Ther. 2014. PMID: 24791939 Free PMC article.

3

Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases.

Yang Y, Xu W, Neill T, Hu Z, Wang CH, Xiao X, Stock SR, Guise T, Yun CO, Brendler CB, Iozzo RV, Seth P. Yang Y, et al. Among authors: xu w. Hum Gene Ther. 2015 Dec;26(12):813-25. doi: 10.1089/hum.2015.098. Epub 2015 Nov 10. Hum Gene Ther. 2015. PMID: 26467629 Free PMC article.

4

SUMO-Specific Cysteine Protease 1 Promotes Epithelial Mesenchymal Transition of Prostate Cancer Cells via Regulating SMAD4 deSUMOylation.

Zhang X, Wang H, Wang H, Xiao F, Seth P, Xu W, Jia Q, Wu C, Yang Y, Wang L. Zhang X, et al. Among authors: xu w. Int J Mol Sci. 2017 Apr 12;18(4):808. doi: 10.3390/ijms18040808. Int J Mol Sci. 2017. PMID: 28417919 Free PMC article.

5

An Oncolytic Adenovirus Encoding Decorin and Granulocyte Macrophage Colony Stimulating Factor Inhibits Tumor Growth in a Colorectal Tumor Model by Targeting Pro-Tumorigenic Signals and via Immune Activation.

Liu Z, Yang Y, Zhang X, Wang H, Xu W, Wang H, Xiao F, Bai Z, Yao H, Ma X, Jin L, Wu C, Seth P, Zhang Z, Wang L. Liu Z, et al. Among authors: xu w. Hum Gene Ther. 2017 Aug;28(8):667-680. doi: 10.1089/hum.2017.033. Hum Gene Ther. 2017. PMID: 28530155

6

Decorin-Modified Umbilical Cord Mesenchymal Stem Cells (MSCs) Attenuate Radiation-Induced Lung Injuries via Regulating Inflammation, Fibrotic Factors, and Immune Responses.

Liu D, Kong F, Yuan Y, Seth P, Xu W, Wang H, Xiao F, Wang L, Zhang Q, Yang Y, Wang H. Liu D, et al. Among authors: xu w. Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):945-956. doi: 10.1016/j.ijrobp.2018.04.007. Epub 2018 Apr 16. Int J Radiat Oncol Biol Phys. 2018. PMID: 29976507

7

Oncolytic Adenovirus rAd.DCN Inhibits Breast Tumor Growth and Lung Metastasis in an Immune-Competent Orthotopic Xenograft Model.

Zhao H, Wang H, Kong F, Xu W, Wang T, Xiao F, Wang L, Huang D, Seth P, Yang Y, Wang H. Zhao H, et al. Among authors: xu w. Hum Gene Ther. 2019 Feb;30(2):197-210. doi: 10.1089/hum.2018.055. Epub 2018 Oct 2. Hum Gene Ther. 2019. PMID: 30032645

8

Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice.

Dai S, Lv Y, Xu W, Yang Y, Liu C, Dong X, Zhang H, Prabhakar BS, Maker AV, Seth P, Wang H. Dai S, et al. Among authors: xu w. Cancer Gene Ther. 2020 Dec;27(12):923-933. doi: 10.1038/s41417-020-0173-z. Epub 2020 Apr 20. Cancer Gene Ther. 2020. PMID: 32307442

9

LyP-1-Modified Oncolytic Adenoviruses Targeting Transforming Growth Factor β Inhibit Tumor Growth and Metastases and Augment Immune Checkpoint Inhibitor Therapy in Breast Cancer Mouse Models.

Xu W, Yang Y, Hu Z, Head M, Mangold KA, Sullivan M, Wang E, Saha P, Gulukota K, Helseth DL, Guise T, Prabhkar BS, Kaul K, Schreiber H, Seth P. Xu W, et al. Hum Gene Ther. 2020 Aug;31(15-16):863-880. doi: 10.1089/hum.2020.078. Epub 2020 Jun 12. Hum Gene Ther. 2020. PMID: 32394753 Free PMC article.

10

The Safety and Efficacy of Systemic Delivery of a New Liver-de-targeted TGFβ Signaling Inhibiting Adenovirus in an Immunocompetent Triple Negative Mouse Mammary Tumor Model.

Xu W, Shin SC, Vickman R, Filimon B, Yang Y, Hu Z, Mangold K, Prabhakar B, Schreiber H. Xu W, et al. Res Sq [Preprint]. 2023 Sep 14:rs.3.rs-3317863. doi: 10.21203/rs.3.rs-3317863/v1. Res Sq. 2023. PMID: 37790556 Free PMC article. Updated. Preprint.

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