Sweeny DJ - Search Results

1

Metabolism of 5-fluorouracil to an N-cholyl-2-fluoro-beta-alanine conjugate: previously unrecognized role for bile acids in drug conjugation.

Sweeny DJ, Barnes S, Heggie GD, Diasio RB. Sweeny DJ, et al. Proc Natl Acad Sci U S A. 1987 Aug;84(15):5439-43. doi: 10.1073/pnas.84.15.5439. Proc Natl Acad Sci U S A. 1987. PMID: 3110788 Free PMC article.

2

2-Fluoro-beta-alanine, a previously unrecognized substrate for bile acid coenzyme A:amino acid:N-acyltransferase from human liver.

Johnson MR, Barnes S, Sweeny DJ, Diasio RB. Johnson MR, et al. Among authors: sweeny dj. Biochem Pharmacol. 1990 Sep 15;40(6):1241-6. doi: 10.1016/0006-2952(90)90389-3. Biochem Pharmacol. 1990. PMID: 2119585

3

Formation of conjugates of 2-fluoro-beta-alanine and bile acids during the metabolism of 5-fluorouracil and 5-fluoro-2-deoxyuridine in the isolated perfused rat liver.

Sweeny DJ, Barnes S, Diasio RB. Sweeny DJ, et al. Cancer Res. 1988 Apr 15;48(8):2010-4. Cancer Res. 1988. PMID: 2964897

4

Bile acid conjugation pattern in the isolated perfused rat liver during infusion of an amino acid formulation.

Sweeny DJ, Barnes S, Diasio RB. Sweeny DJ, et al. JPEN J Parenter Enteral Nutr. 1991 May-Jun;15(3):303-6. doi: 10.1177/0148607191015003303. JPEN J Parenter Enteral Nutr. 1991. PMID: 1907679

5

Biological properties of the 2-fluoro-beta-alanine conjugates of cholic acid and chenodeoxycholic acid in the isolated perfused rat liver.

Sweeny DJ, Daher G, Barnes S, Diasio RB. Sweeny DJ, et al. Biochim Biophys Acta. 1990 Aug 13;1054(1):21-5. doi: 10.1016/0167-4889(90)90200-w. Biochim Biophys Acta. 1990. PMID: 2116908

6

N-chenodeoxycholyl-2-fluoro-beta-alanine: a biliary metabolite of 5-fluorouracil in humans.

Sweeny DJ, Martin M, Diasio RB. Sweeny DJ, et al. Drug Metab Dispos. 1988 Nov-Dec;16(6):892-4. Drug Metab Dispos. 1988. PMID: 2907471 No abstract available.

7

Single- and multiple-dose disposition kinetics of sunitinib malate, a multitargeted receptor tyrosine kinase inhibitor: comparative plasma kinetics in non-clinical species.

Haznedar JO, Patyna S, Bello CL, Peng GW, Speed W, Yu X, Zhang Q, Sukbuntherng J, Sweeny DJ, Antonian L, Wu EY. Haznedar JO, et al. Among authors: sweeny dj. Cancer Chemother Pharmacol. 2009 Sep;64(4):691-706. doi: 10.1007/s00280-008-0917-1. Epub 2009 Jan 25. Cancer Chemother Pharmacol. 2009. PMID: 19169880

8

Sulfation of acetaminophen in isolated rat hepatocytes. Relationship to sulfate ion concentrations and intracellular levels of 3'-phosphoadenosine-5'-phosphosulfate.

Sweeny DJ, Reinke LA. Sweeny DJ, et al. Drug Metab Dispos. 1988 Sep-Oct;16(5):712-5. Drug Metab Dispos. 1988. PMID: 2906595

9

Enantiomeric activation of glucuronidation in dog hepatic microsomes.

Sweeny DJ, Nellans HN. Sweeny DJ, et al. J Biol Chem. 1992 Jul 5;267(19):13171-4. J Biol Chem. 1992. PMID: 1618819 Free article.

10

Stereoselective glucuronidation of zileuton isomers by human hepatic microsomes.

Sweeny DJ, Nellans HN. Sweeny DJ, et al. Drug Metab Dispos. 1995 Jan;23(1):149-53. Drug Metab Dispos. 1995. PMID: 7720519

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