Shrestha R - Search Results

1

Structure-dependent activation of gene expression by bis-indole and quinoline-derived activators of nuclear receptor 4A2.

Li X, Tjalkens RB, Shrestha R, Safe S. Li X, et al. Among authors: shrestha r. Chem Biol Drug Des. 2019 Oct;94(4):1711-1720. doi: 10.1111/cbdd.13564. Epub 2019 Jul 21. Chem Biol Drug Des. 2019. PMID: 31102570 Free PMC article. Review.

2

Omeprazole Inhibits Glioblastoma Cell Invasion and Tumor Growth.

Jin UH, Michelhaugh SK, Polin LA, Shrestha R, Mittal S, Safe S. Jin UH, et al. Among authors: shrestha r. Cancers (Basel). 2020 Jul 28;12(8):2097. doi: 10.3390/cancers12082097. Cancers (Basel). 2020. PMID: 32731514 Free PMC article.

3

Bis-indole derived nuclear receptor 4A1 (NR4A1) antagonists inhibit TGFβ-induced invasion of embryonal rhabdomyosarcoma cells.

Shrestha R, Mohankumar K, Safe S. Shrestha R, et al. Am J Cancer Res. 2020 Aug 1;10(8):2495-2509. eCollection 2020. Am J Cancer Res. 2020. PMID: 32905449 Free PMC article.

4

The Histone Methyltransferase Gene G9A Is Regulated by Nuclear Receptor 4A1 in Alveolar Rhabdomyosarcoma Cells.

Shrestha R, Mohankumar K, Jin UH, Martin G, Safe S. Shrestha R, et al. Mol Cancer Ther. 2021 Mar;20(3):612-622. doi: 10.1158/1535-7163.MCT-20-0474. Epub 2020 Dec 4. Mol Cancer Ther. 2021. PMID: 33277444 Free PMC article.

5

Flavonoids: structure-function and mechanisms of action and opportunities for drug development.

Safe S, Jayaraman A, Chapkin RS, Howard M, Mohankumar K, Shrestha R. Safe S, et al. Among authors: shrestha r. Toxicol Res. 2021 Jan 20;37(2):147-162. doi: 10.1007/s43188-020-00080-z. eCollection 2021 Apr. Toxicol Res. 2021. PMID: 33868973 Free PMC article. Review.

6

NR4A1 Ligands as Potent Inhibitors of Breast Cancer Cell and Tumor Growth.

Karki K, Mohankumar K, Schoeller A, Martin G, Shrestha R, Safe S. Karki K, et al. Among authors: shrestha r. Cancers (Basel). 2021 May 29;13(11):2682. doi: 10.3390/cancers13112682. Cancers (Basel). 2021. PMID: 34072371 Free PMC article.

7

Orphan nuclear receptor 4A1 (NR4A1) and novel ligands.

Safe S, Shrestha R, Mohankumar K. Safe S, et al. Among authors: shrestha r. Essays Biochem. 2021 Dec 17;65(6):877-886. doi: 10.1042/EBC20200164. Essays Biochem. 2021. PMID: 34096590

8

Nuclear receptor 4A1 (NR4A1) antagonists target paraspeckle component 1 (PSPC1) in cancer cells.

Mohankumar K, Shrestha R, Safe S. Mohankumar K, et al. Among authors: shrestha r. Mol Carcinog. 2022 Jan;61(1):73-84. doi: 10.1002/mc.23362. Epub 2021 Oct 26. Mol Carcinog. 2022. PMID: 34699643 Free PMC article.

9

Transcription factors specificity protein and nuclear receptor 4A1 in pancreatic cancer.

Safe S, Shrestha R, Mohankumar K, Howard M, Hedrick E, Abdelrahim M. Safe S, et al. Among authors: shrestha r. World J Gastroenterol. 2021 Oct 14;27(38):6387-6398. doi: 10.3748/wjg.v27.i38.6387. World J Gastroenterol. 2021. PMID: 34720529 Free PMC article. Review.

10

Flavonoids kaempferol and quercetin are nuclear receptor 4A1 (NR4A1, Nur77) ligands and inhibit rhabdomyosarcoma cell and tumor growth.

Shrestha R, Mohankumar K, Martin G, Hailemariam A, Lee SO, Jin UH, Burghardt R, Safe S. Shrestha R, et al. J Exp Clin Cancer Res. 2021 Dec 14;40(1):392. doi: 10.1186/s13046-021-02199-9. J Exp Clin Cancer Res. 2021. PMID: 34906197 Free PMC article.

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