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Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive protection across divergent subgroups.
Hutchinson G, Abiona O, Ziwawo C, Werner A, Ellis D, Tsybovsky Y, Leist S, Palandjian C, West A, Fritch E, Wang N, Wrapp D, Boyoglu-Barnum S, Ueda G, Baker D, Kanekiyo M, McLellan J, Baric R, King N, Graham B, Corbett K. Hutchinson G, et al. Res Sq [Preprint]. 2022 Nov 7:rs.3.rs-2199814. doi: 10.21203/rs.3.rs-2199814/v1. Res Sq. 2022. PMID: 36380759 Free PMC article. Updated. Preprint.
Extremely potent pan-sarbecovirus neutralizing antibodies generated by immunization of macaques with an AS03-adjuvanted monovalent subunit vaccine against SARS-CoV-2.
Feng Y, Yuan M, Powers JM, Hu M, Munt JE, Arunachalam PS, Leist SR, Bellusci L, Adams LE, Sundaramurthy S, Shirreff LM, Mallory ML, Scooby TD, Moreno A, O'Hagan DT, Kleanthous H, Villinger FJ, Veesler D, King NP, Suthar MS, Khurana S, Baric RS, Wilson IA, Pulendran B. Feng Y, et al. Among authors: leist sr. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524784. doi: 10.1101/2023.01.19.524784. bioRxiv. 2023. PMID: 36711543 Free PMC article. Preprint.
Host range, transmissibility and antigenicity of a pangolin coronavirus.
Hou YJ, Chiba S, Leist SR, Meganck RM, Martinez DR, Schäfer A, Catanzaro NJ, Sontake V, West A, Edwards CE, Yount B, Lee RE, Gallant SC, Zost SJ, Powers J, Adams L, Kong EF, Mattocks M, Tata A, Randell SH, Tata PR, Halfmann P, Crowe JE Jr, Kawaoka Y, Baric RS. Hou YJ, et al. Among authors: leist sr. Nat Microbiol. 2023 Oct;8(10):1820-1833. doi: 10.1038/s41564-023-01476-x. Epub 2023 Sep 25. Nat Microbiol. 2023. PMID: 37749254 Free PMC article.
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Feng Y, Yuan M, Powers JM, Hu M, Munt JE, Arunachalam PS, Leist SR, Bellusci L, Kim J, Sprouse KR, Adams LE, Sundaramurthy S, Zhu X, Shirreff LM, Mallory ML, Scobey TD, Moreno A, O'Hagan DT, Kleanthous H, Villinger FJ, Veesler D, King NP, Suthar MS, Khurana S, Baric RS, Wilson IA, Pulendran B. Feng Y, et al. Among authors: leist sr. Sci Transl Med. 2023 May 10;15(695):eadg7404. doi: 10.1126/scitranslmed.adg7404. Epub 2023 May 10. Sci Transl Med. 2023. PMID: 37163615 Free PMC article.
Human coronavirus OC43-elicited CD4+ T cells protect against SARS-CoV-2 in HLA transgenic mice.
Dos Santos Alves RP, Timis J, Miller R, Valentine K, Pinto PBA, Gonzalez A, Regla-Nava JA, Maule E, Nguyen MN, Shafee N, Landeras-Bueno S, Olmedillas E, Laffey B, Dobaczewska K, Mikulski Z, McArdle S, Leist SR, Kim K, Baric RS, Ollmann Saphire E, Elong Ngono A, Shresta S. Dos Santos Alves RP, et al. Among authors: leist sr. Nat Commun. 2024 Jan 26;15(1):787. doi: 10.1038/s41467-024-45043-2. Nat Commun. 2024. PMID: 38278784 Free PMC article.
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