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Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma.
Lupino L, Perry T, Margielewska S, Hollows R, Ibrahim M, Care M, Allegood J, Tooze R, Sabbadini R, Reynolds G, Bicknell R, Rudzki Z, Lin Hock Y, Zanetto U, Wei W, Simmons W, Spiegel S, Woodman CBJ, Rowe M, Vrzalikova K, Murray PG. Lupino L, et al. Among authors: allegood j. Leukemia. 2019 Dec;33(12):2884-2897. doi: 10.1038/s41375-019-0478-9. Epub 2019 May 16. Leukemia. 2019. PMID: 31097785 Free PMC article.
S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells.
Vrzalikova K, Ibrahim M, Vockerodt M, Perry T, Margielewska S, Lupino L, Nagy E, Soilleux E, Liebelt D, Hollows R, Last A, Reynolds G, Abdullah M, Curley H, Care M, Krappmann D, Tooze R, Allegood J, Spiegel S, Wei W, Woodman CBJ, Murray PG. Vrzalikova K, et al. Among authors: allegood j. Leukemia. 2018 Jan;32(1):214-223. doi: 10.1038/leu.2017.275. Epub 2017 Sep 7. Leukemia. 2018. PMID: 28878352 Free PMC article.
Correction: S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells.
Vrzalikova K, Ibrahim M, Vockerodt M, Perry T, Margielewska S, Lupino L, Nagy E, Soilleux E, Liebelt D, Hollows R, Last A, Reynolds G, Abdullah M, Curley H, Care M, Krappmann D, Tooze R, Allegood J, Spiegel S, Wei W, Woodman CBJ, Murray PG. Vrzalikova K, et al. Among authors: allegood j. Leukemia. 2019 Aug;33(8):2126. doi: 10.1038/s41375-019-0511-z. Leukemia. 2019. PMID: 31239494 Free PMC article.
Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage.
Lépine S, Allegood JC, Edmonds Y, Milstien S, Spiegel S. Lépine S, et al. J Biol Chem. 2011 Dec 30;286(52):44380-90. doi: 10.1074/jbc.M111.257519. Epub 2011 Nov 3. J Biol Chem. 2011. PMID: 22052905 Free PMC article.
Depletion of S1P phosphohydrolase-1 (SPP1), which degrades intracellular S1P, induces the unfolded protein response and endoplasmic reticulum stress-induced autophagy (Lepine, S., Allegood, J. C., Park, M., Dent, P., Milstien, S., and Spiegel, S. (2011) Cell Death D …
Depletion of S1P phosphohydrolase-1 (SPP1), which degrades intracellular S1P, induces the unfolded protein response and endoplasmic reticulu …
Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer.
Liang J, Nagahashi M, Kim EY, Harikumar KB, Yamada A, Huang WC, Hait NC, Allegood JC, Price MM, Avni D, Takabe K, Kordula T, Milstien S, Spiegel S. Liang J, et al. Among authors: allegood jc. Cancer Cell. 2013 Jan 14;23(1):107-20. doi: 10.1016/j.ccr.2012.11.013. Epub 2012 Dec 27. Cancer Cell. 2013. PMID: 23273921 Free PMC article.
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate.
Hait NC, Allegood J, Maceyka M, Strub GM, Harikumar KB, Singh SK, Luo C, Marmorstein R, Kordula T, Milstien S, Spiegel S. Hait NC, et al. Among authors: allegood j. Science. 2009 Sep 4;325(5945):1254-7. doi: 10.1126/science.1176709. Science. 2009. PMID: 19729656 Free PMC article.
93 results