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Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.
Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, Wan L, Shen C, Hsu CH, Papa A, Clohessy JG, Teruya-Feldstein J, Jain S, Wu H, Matesic L, Chen RH, Wei W, Pandolfi PP. Lee YR, et al. Among authors: fu tm. Science. 2019 May 17;364(6441):eaau0159. doi: 10.1126/science.aau0159. Science. 2019. PMID: 31097636 Free PMC article.
Structural biology of innate immunity.
Yin Q, Fu TM, Li J, Wu H. Yin Q, et al. Among authors: fu tm. Annu Rev Immunol. 2015;33:393-416. doi: 10.1146/annurev-immunol-032414-112258. Epub 2015 Jan 22. Annu Rev Immunol. 2015. PMID: 25622194 Free PMC article. Review.
Mechanism of ubiquitin transfer promoted by TRAF6.
Fu TM, Shen C, Li Q, Zhang P, Wu H. Fu TM, et al. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1783-1788. doi: 10.1073/pnas.1721788115. Epub 2018 Feb 5. Proc Natl Acad Sci U S A. 2018. PMID: 29432170 Free PMC article.
Structures and gating mechanism of human TRPM2.
Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Wang L, et al. Among authors: fu tm. Science. 2018 Dec 21;362(6421):eaav4809. doi: 10.1126/science.aav4809. Epub 2018 Nov 22. Science. 2018. PMID: 30467180 Free PMC article.
Molecular mechanism for NLRP6 inflammasome assembly and activation.
Shen C, Lu A, Xie WJ, Ruan J, Negro R, Egelman EH, Fu TM, Wu H. Shen C, et al. Among authors: fu tm. Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2052-2057. doi: 10.1073/pnas.1817221116. Epub 2019 Jan 23. Proc Natl Acad Sci U S A. 2019. PMID: 30674671 Free PMC article.
215 results