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Ribonucleotides in mitochondrial DNA.
Wanrooij PH, Chabes A. Wanrooij PH, et al. Among authors: chabes a. FEBS Lett. 2019 Jul;593(13):1554-1565. doi: 10.1002/1873-3468.13440. Epub 2019 May 24. FEBS Lett. 2019. PMID: 31093968 Free article. Review.
Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired.
Wanrooij PH, Engqvist MKM, Forslund JME, Navarrete C, Nilsson AK, Sedman J, Wanrooij S, Clausen AR, Chabes A. Wanrooij PH, et al. Among authors: chabes a. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12466-12471. doi: 10.1073/pnas.1713085114. Epub 2017 Nov 6. Proc Natl Acad Sci U S A. 2017. PMID: 29109257 Free PMC article.
De novo dNTP production is essential for normal postnatal murine heart development.
Tran P, Wanrooij PH, Lorenzon P, Sharma S, Thelander L, Nilsson AK, Olofsson AK, Medini P, von Hofsten J, Stål P, Chabes A. Tran P, et al. Among authors: chabes a. J Biol Chem. 2019 Nov 1;294(44):15889-15897. doi: 10.1074/jbc.RA119.009492. Epub 2019 Jul 12. J Biol Chem. 2019. PMID: 31300555 Free PMC article.
Elimination of rNMPs from mitochondrial DNA has no effect on its stability.
Wanrooij PH, Tran P, Thompson LJ, Carvalho G, Sharma S, Kreisel K, Navarrete C, Feldberg AL, Watt DL, Nilsson AK, Engqvist MKM, Clausen AR, Chabes A. Wanrooij PH, et al. Among authors: chabes a. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14306-14313. doi: 10.1073/pnas.1916851117. Epub 2020 Jun 8. Proc Natl Acad Sci U S A. 2020. PMID: 32513727 Free PMC article.
Genome instability due to ribonucleotide incorporation into DNA.
Nick McElhinny SA, Kumar D, Clark AB, Watt DL, Watts BE, Lundström EB, Johansson E, Chabes A, Kunkel TA. Nick McElhinny SA, et al. Among authors: chabes a. Nat Chem Biol. 2010 Oct;6(10):774-81. doi: 10.1038/nchembio.424. Epub 2010 Aug 22. Nat Chem Biol. 2010. PMID: 20729855 Free PMC article.
91 results