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Functional Analysis of HDACs in Tumorigenesis.
Hadley M, Noonepalle S, Banik D, Villagra A. Hadley M, et al. Among authors: villagra a. Methods Mol Biol. 2019;1983:279-307. doi: 10.1007/978-1-4939-9434-2_17. Methods Mol Biol. 2019. PMID: 31087305 Review.
Functional Analysis of Histone Deacetylase 11 (HDAC11).
Chen J, Sahakian E, Powers J, Lienlaf M, Perez-Villarroel P, Knox T, Villagra A. Chen J, et al. Among authors: villagra a. Methods Mol Biol. 2016;1436:147-65. doi: 10.1007/978-1-4939-3667-0_11. Methods Mol Biol. 2016. PMID: 27246214 Free PMC article.
Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells.
Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, Kim J, Powers J, Gracia-Hernandez M, Oliveira V, Cheng F, Chen J, Barinka C, Pinilla-Ibarz J, Lee NH, Kozikowski A, Villagra A. Knox T, et al. Among authors: villagra a. Sci Rep. 2019 Apr 16;9(1):6136. doi: 10.1038/s41598-019-42237-3. Sci Rep. 2019. PMID: 30992475 Free PMC article.
Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models.
Shen S, Hadley M, Ustinova K, Pavlicek J, Knox T, Noonepalle S, Tavares MT, Zimprich CA, Zhang G, Robers MB, Bařinka C, Kozikowski AP, Villagra A. Shen S, et al. Among authors: villagra a. J Med Chem. 2019 Sep 26;62(18):8557-8577. doi: 10.1021/acs.jmedchem.9b00946. Epub 2019 Sep 4. J Med Chem. 2019. PMID: 31414801
Author Correction: Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells.
Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, Kim J, Powers J, Gracia-Hernandez M, Oliveira V, Cheng F, Chen J, Barinka C, Pinilla-Ibarz J, Lee NH, Kozikowski A, Villagra A. Knox T, et al. Among authors: villagra a. Sci Rep. 2019 Oct 10;9(1):14824. doi: 10.1038/s41598-019-51403-6. Sci Rep. 2019. PMID: 31597938 Free PMC article.
156 results