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Treatment of Primary Aldosteronism With mTORC1 Inhibitors.
Trinh B, Hepprich M, Betz MJ, Burkard T, Cavelti-Weder C, Seelig E, Meienberg F, Kratschmar DV, Beuschlein F, Reincke M, Odermatt A, Hall MN, Donath MY, Swierczynska MM. Trinh B, et al. Among authors: hall mn. J Clin Endocrinol Metab. 2019 Oct 1;104(10):4703-4714. doi: 10.1210/jc.2019-00563. J Clin Endocrinol Metab. 2019. PMID: 31087053 Clinical Trial.
An amino acid shuffle activates mTORC1.
Cohen A, Hall MN. Cohen A, et al. Among authors: hall mn. Cell. 2009 Feb 6;136(3):399-400. doi: 10.1016/j.cell.2009.01.021. Cell. 2009. PMID: 19203575 Free article.
Multiple amino acid sensing inputs to mTORC1.
Shimobayashi M, Hall MN. Shimobayashi M, et al. Among authors: hall mn. Cell Res. 2016 Jan;26(1):7-20. doi: 10.1038/cr.2015.146. Epub 2015 Dec 11. Cell Res. 2016. PMID: 26658722 Free PMC article. Review.
eIF4A moonlights as an off switch for TORC1.
Swierczynska MM, Hall MN. Swierczynska MM, et al. Among authors: hall mn. EMBO J. 2016 May 17;35(10):1013-4. doi: 10.15252/embj.201694326. Epub 2016 Apr 4. EMBO J. 2016. PMID: 27044920 Free PMC article.
mTORC1 Controls Synthesis of Its Activator GTP.
Benjamin D, Hall MN. Benjamin D, et al. Among authors: hall mn. Cell Rep. 2017 Jun 27;19(13):2643-2644. doi: 10.1016/j.celrep.2017.06.032. Cell Rep. 2017. PMID: 28658613 Free article. Review.
Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.
Bozadjieva N, Blandino-Rosano M, Chase J, Dai XQ, Cummings K, Gimeno J, Dean D, Powers AC, Gittes GK, Rüegg MA, Hall MN, MacDonald PE, Bernal-Mizrachi E. Bozadjieva N, et al. Among authors: hall mn. J Clin Invest. 2017 Dec 1;127(12):4379-4393. doi: 10.1172/JCI90004. Epub 2017 Nov 6. J Clin Invest. 2017. PMID: 29106387 Free PMC article.
Architecture of the human mTORC2 core complex.
Stuttfeld E, Aylett CH, Imseng S, Boehringer D, Scaiola A, Sauer E, Hall MN, Maier T, Ban N. Stuttfeld E, et al. Among authors: hall mn. Elife. 2018 Feb 9;7:e33101. doi: 10.7554/eLife.33101. Elife. 2018. PMID: 29424687 Free PMC article.
345 results