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Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.
Chitty JL, Blake KL, Blundell RD, Koh YQAE, Thompson M, Robertson AAB, Butler MS, Cooper MA, Kappler U, Williams SJ, Kobe B, Fraser JA. Chitty JL, et al. Among authors: fraser ja. J Biol Chem. 2017 Jul 14;292(28):11829-11839. doi: 10.1074/jbc.M117.787994. Epub 2017 May 30. J Biol Chem. 2017. PMID: 28559277 Free PMC article.
Antimicrobial Octapeptin C4 Analogues Active against Cryptococcus Species.
Chitty JL, Butler MS, Suboh A, Edwards DJ, Cooper MA, Fraser JA, Robertson AAB. Chitty JL, et al. Among authors: fraser ja. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e00986-17. doi: 10.1128/AAC.00986-17. Print 2018 Feb. Antimicrob Agents Chemother. 2018. PMID: 29158283 Free PMC article.
308 results