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Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma.
Xie JJ, Jiang YY, Jiang Y, Li CQ, Lim MC, An O, Mayakonda A, Ding LW, Long L, Sun C, Lin LH, Chen L, Wu JY, Wu ZY, Cao Q, Fang WK, Yang W, Soukiasian H, Meltzer SJ, Yang H, Fullwood M, Xu LY, Li EM, Lin DC, Koeffler HP. Xie JJ, et al. Among authors: an o. Gastroenterology. 2018 Jun;154(8):2137-2151.e1. doi: 10.1053/j.gastro.2018.02.018. Epub 2018 Feb 15. Gastroenterology. 2018. PMID: 29454790
Identification of a novel enhancer of CEBPE essential for granulocytic differentiation.
Shyamsunder P, Shanmugasundaram M, Mayakonda A, Dakle P, Teoh WW, Han L, Kanojia D, Lim MC, Fullwood M, An O, Yang H, Shi J, Hossain MZ, Madan V, Koeffler HP. Shyamsunder P, et al. Among authors: an o. Blood. 2019 Jun 6;133(23):2507-2517. doi: 10.1182/blood.2018886077. Epub 2019 Apr 5. Blood. 2019. PMID: 30952671 Free article.
p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain).
Teoh PJ, An O, Chung TH, Vaiyapuri T, Raju A, Hoppe MM, Toh SHM, Wang W, Chan MC, Fullwood MJ, Jeyasekharan AD, Tergaonkar V, Chen L, Yang H, Chng WJ. Teoh PJ, et al. Among authors: an o. Oncogene. 2022 Apr;41(14):2106-2121. doi: 10.1038/s41388-022-02227-8. Epub 2022 Feb 21. Oncogene. 2022. PMID: 35190641
Pan-cancer pervasive upregulation of 3' UTR splicing drives tumourigenesis.
Chan JJ, Zhang B, Chew XH, Salhi A, Kwok ZH, Lim CY, Desi N, Subramaniam N, Siemens A, Kinanti T, Ong S, Sanchez-Mejias A, Ly PT, An O, Sundar R, Fan X, Wang S, Siew BE, Lee KC, Chong CS, Lieske B, Cheong WK, Goh Y, Fam WN, Ooi MG, Koh BTH, Iyer SG, Ling WH, Chen J, Yoong BK, Chanwat R, Bonney GK, Goh BKP, Zhai W, Fullwood MJ, Wang W, Tan KK, Chng WJ, Dan YY, Pitt JJ, Roca X, Guccione E, Vardy LA, Chen L, Gao X, Chow PKH, Yang H, Tay Y. Chan JJ, et al. Among authors: an o. Nat Cell Biol. 2022 Jun;24(6):928-939. doi: 10.1038/s41556-022-00913-z. Epub 2022 May 26. Nat Cell Biol. 2022. PMID: 35618746 Free PMC article.
Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis.
Guo M, Chan THM, Zhou Q, An O, Li Y, Song Y, Tan ZH, Ng VHE, Peramangalam PS, Tan ZQ, Cao X, Iwanaga E, Matsuoka M, Ooi MGM, Jen WY, Koh LP, Chan E, Tan LK, Goh Y, Wang W, Koh BTH, Chun CM, Fullwood MJ, Chng WJ, Osato M, Pulikkan JA, Yang H, Chen L, Tenen DG. Guo M, et al. Among authors: an o. Blood. 2023 Jun 22;141(25):3078-3090. doi: 10.1182/blood.2022015830. Blood. 2023. PMID: 36796022
T and NK cell lymphoma cell lines do not rely on ZAP-70 for survival.
de Mel S, Mustafa N, Selvarajan V, Azaman MI, Jaynes PW, Venguidessane S, Phuong HM, Alnaseri ZT, Phyu T, Girard LP, Chng WJ, Wardyn J, Li Y, An O, Yang H, Ng SB, Jeyasekharan AD. de Mel S, et al. Among authors: an o. PLoS One. 2022 Jan 25;17(1):e0261469. doi: 10.1371/journal.pone.0261469. eCollection 2022. PLoS One. 2022. PMID: 35077445 Free PMC article.
42 results