Hultgren SJ - Search Results

1

Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis.

Flentie K, Harrison GA, Tükenmez H, Livny J, Good JAD, Sarkar S, Zhu DX, Kinsella RL, Weiss LA, Solomon SD, Schene ME, Hansen MR, Cairns AG, Kulén M, Wixe T, Lindgren AEG, Chorell E, Bengtsson C, Krishnan KS, Hultgren SJ, Larsson C, Almqvist F, Stallings CL. Flentie K, et al. Among authors: hultgren sj. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10510-10517. doi: 10.1073/pnas.1818009116. Epub 2019 May 6. Proc Natl Acad Sci U S A. 2019. PMID: 31061116 Free PMC article.

2

Stereoselective synthesis of optically active beta-lactams, potential inhibitors of pilus assembly in pathogenic bacteria.

Emtenäs H, Soto G, Hultgren SJ, Marshall GR, Almqvist F. Emtenäs H, et al. Among authors: hultgren sj. Org Lett. 2000 Jul 13;2(14):2065-7. doi: 10.1021/ol0059899. Org Lett. 2000. PMID: 10891231

3

Design and parallel solid-phase synthesis of ring-fused 2-pyridinones that target pilus biogenesis in pathogenic bacteria.

Emtenäs H, Ahlin K, Pinkner JS, Hultgren SJ, Almqvist F. Emtenäs H, et al. Among authors: hultgren sj. J Comb Chem. 2002 Nov-Dec;4(6):630-9. doi: 10.1021/cc020032d. J Comb Chem. 2002. PMID: 12425608

4

Toll-like receptor 4 on stromal and hematopoietic cells mediates innate resistance to uropathogenic Escherichia coli.

Schilling JD, Martin SM, Hung CS, Lorenz RG, Hultgren SJ. Schilling JD, et al. Among authors: hultgren sj. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4203-8. doi: 10.1073/pnas.0736473100. Epub 2003 Mar 24. Proc Natl Acad Sci U S A. 2003. PMID: 12655047 Free PMC article.

5

Stereoselective synthesis of optically active bicyclic beta-lactam carboxylic acids that target pilus biogenesis in pathogenic bacteria.

Emtenäs H, Carlsson M, Pinkner JS, Hultgren SJ, Almqvist F. Emtenäs H, et al. Among authors: hultgren sj. Org Biomol Chem. 2003 Apr 21;1(8):1308-14. doi: 10.1039/b210551a. Org Biomol Chem. 2003. PMID: 12929660

6

Targeting virulence for antimicrobial chemotherapy.

Lee YM, Almqvist F, Hultgren SJ. Lee YM, et al. Among authors: hultgren sj. Curr Opin Pharmacol. 2003 Oct;3(5):513-9. doi: 10.1016/j.coph.2003.04.001. Curr Opin Pharmacol. 2003. PMID: 14559097 Review.

7

Multivariate design, synthesis, and biological evaluation of peptide inhibitors of FimC/FimH protein-protein interactions in uropathogenic Escherichia coli.

Larsson A, Johansson SM, Pinkner JS, Hultgren SJ, Almqvist F, Kihlberg J, Linusson A. Larsson A, et al. Among authors: hultgren sj. J Med Chem. 2005 Feb 24;48(4):935-45. doi: 10.1021/jm040818l. J Med Chem. 2005. PMID: 15715464

8

C-Terminal properties are important for ring-fused 2-pyridones that interfere with the chaperone function in uropathogenic E. coli.

Aberg V, Hedenström M, Pinkner JS, Hultgren SJ, Almqvist F. Aberg V, et al. Among authors: hultgren sj. Org Biomol Chem. 2005 Nov 7;3(21):3886-92. doi: 10.1039/b509376g. Epub 2005 Sep 5. Org Biomol Chem. 2005. PMID: 16240004

9

NMR studies of interactions between periplasmic chaperones from uropathogenic E. coli and pilicides that interfere with chaperone function and pilus assembly.

Hedenström M, Emtenäs H, Pemberton N, Aberg V, Hultgren SJ, Pinkner JS, Tegman V, Almqvist F, Sethson I, Kihlberg J. Hedenström M, et al. Among authors: hultgren sj. Org Biomol Chem. 2005 Dec 7;3(23):4193-200. doi: 10.1039/b511857c. Epub 2005 Oct 31. Org Biomol Chem. 2005. PMID: 16294247

10

Design, synthesis and evaluation of peptidomimetics based on substituted bicyclic 2-pyridones-targeting virulence of uropathogenic E. coli.

Berg V, Sellstedt M, Hedenström M, Pinkner JS, Hultgren SJ, Almqvist F. Berg V, et al. Among authors: hultgren sj. Bioorg Med Chem. 2006 Nov 15;14(22):7563-81. doi: 10.1016/j.bmc.2006.07.017. Epub 2006 Aug 14. Bioorg Med Chem. 2006. PMID: 16904898

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