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Page 1
Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis.
Flentie K, Harrison GA, Tükenmez H, Livny J, Good JAD, Sarkar S, Zhu DX, Kinsella RL, Weiss LA, Solomon SD, Schene ME, Hansen MR, Cairns AG, Kulén M, Wixe T, Lindgren AEG, Chorell E, Bengtsson C, Krishnan KS, Hultgren SJ, Larsson C, Almqvist F, Stallings CL. Flentie K, et al. Among authors: good jad. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10510-10517. doi: 10.1073/pnas.1818009116. Epub 2019 May 6. Proc Natl Acad Sci U S A. 2019. PMID: 31061116 Free PMC article.
Synthesis of fluorescent ring-fused 2-pyridone peptidomimetics.
Krishnan KS, Bengtsson C, Good JA, Mirkhanov S, Chorell E, Johansson LB, Almqvist F. Krishnan KS, et al. J Org Chem. 2013 Dec 6;78(23):12207-13. doi: 10.1021/jo401844y. Epub 2013 Nov 14. J Org Chem. 2013. PMID: 24161000
Thiazolino 2-Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity.
Good JA, Silver J, Núñez-Otero C, Bahnan W, Krishnan KS, Salin O, Engström P, Svensson R, Artursson P, Gylfe Å, Bergström S, Almqvist F. Good JA, et al. J Med Chem. 2016 Mar 10;59(5):2094-108. doi: 10.1021/acs.jmedchem.5b01759. Epub 2016 Feb 22. J Med Chem. 2016. PMID: 26849778
Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA.
Good JA, Andersson C, Hansen S, Wall J, Krishnan KS, Begum A, Grundström C, Niemiec MS, Vaitkevicius K, Chorell E, Wittung-Stafshede P, Sauer UH, Sauer-Eriksson AE, Almqvist F, Johansson J. Good JA, et al. Cell Chem Biol. 2016 Mar 17;23(3):404-14. doi: 10.1016/j.chembiol.2016.02.013. Cell Chem Biol. 2016. PMID: 26991105 Free PMC article.
Methyl sulfonamide substituents improve the pharmacokinetic properties of bicyclic 2-pyridone based Chlamydia trachomatis inhibitors.
Kulén M, Núñez-Otero C, Cairns AG, Silver J, Lindgren AEG, Wede E, Singh P, Vielfort K, Bahnan W, Good JAD, Svensson R, Bergström S, Gylfe Å, Almqvist F. Kulén M, et al. Among authors: good jad. Medchemcomm. 2019 Oct 17;10(11):1966-1987. doi: 10.1039/c9md00405j. eCollection 2019 Nov 1. Medchemcomm. 2019. PMID: 32206238 Free PMC article.
Design, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant.
Sarkar S, Mayer Bridwell AE, Good JAD, Wang ER, McKee SR, Valenta J, Harrison GA, Flentie KN, Henry FL, Wixe T, Demirel P, Vagolu SK, Chatagnon J, Machelart A, Brodin P, Tønjum T, Stallings CL, Almqvist F. Sarkar S, et al. Among authors: good jad. J Med Chem. 2023 Aug 24;66(16):11056-11077. doi: 10.1021/acs.jmedchem.3c00358. Epub 2023 Jul 24. J Med Chem. 2023. PMID: 37485869 Free PMC article.
Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system.
Varga MG, Shaffer CL, Sierra JC, Suarez G, Piazuelo MB, Whitaker ME, Romero-Gallo J, Krishna US, Delgado A, Gomez MA, Good JA, Almqvist F, Skaar EP, Correa P, Wilson KT, Hadjifrangiskou M, Peek RM. Varga MG, et al. Oncogene. 2016 Dec 1;35(48):6262-6269. doi: 10.1038/onc.2016.158. Epub 2016 May 9. Oncogene. 2016. PMID: 27157617 Free PMC article.
17 results