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TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells.
Arhatte M, Gunaratne GS, El Boustany C, Kuo IY, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-Gervais S, Ehrlich BE, Marchant JS, Savage AM, van Eeden FJM, Wilkinson RN, Demolombe S, Honoré E, Patel A. Arhatte M, et al. Among authors: patel a. Nat Commun. 2019 May 2;10(1):2024. doi: 10.1038/s41467-019-10045-y. Nat Commun. 2019. PMID: 31048699 Free PMC article.
Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK.
Maingret F, Patel AJ, Lesage F, Lazdunski M, Honoré E. Maingret F, et al. Among authors: patel aj. J Biol Chem. 2000 Apr 7;275(14):10128-33. doi: 10.1074/jbc.275.14.10128. J Biol Chem. 2000. PMID: 10744694 Free article.
The two-pore (2P) domain K(+) channels TREK-1 and TRAAK are opened by membrane stretch as well as arachidonic acid (AA) (Patel, A. J., Honore, E., Maingret, F., Lesage, F., Fink, M., Duprat, F., and Lazdunski, M. (1998) EMBO J. 17, 4283-4290; Maingret, F., Patel …
The two-pore (2P) domain K(+) channels TREK-1 and TRAAK are opened by membrane stretch as well as arachidonic acid (AA) (Patel, A …
TREK-1 is a heat-activated background K(+) channel.
Maingret F, Lauritzen I, Patel AJ, Heurteaux C, Reyes R, Lesage F, Lazdunski M, Honoré E. Maingret F, et al. Among authors: patel aj. EMBO J. 2000 Jun 1;19(11):2483-91. doi: 10.1093/emboj/19.11.2483. EMBO J. 2000. PMID: 10835347 Free PMC article.
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