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The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State.
Yoo JH, Brady SW, Acosta-Alvarez L, Rogers A, Peng J, Sorensen LK, Wolff RK, Mleynek T, Shin D, Rich CP, Kircher DA, Bild A, Odelberg SJ, Li DY, Holmen SL, Grossmann AH. Yoo JH, et al. Among authors: holmen sl. Cancer Res. 2019 Jun 1;79(11):2892-2908. doi: 10.1158/0008-5472.CAN-18-3026. Epub 2019 May 2. Cancer Res. 2019. PMID: 31048499 Free PMC article.
AKT1 Activation Promotes Development of Melanoma Metastases.
Cho JH, Robinson JP, Arave RA, Burnett WJ, Kircher DA, Chen G, Davies MA, Grossmann AH, VanBrocklin MW, McMahon M, Holmen SL. Cho JH, et al. Among authors: holmen sl. Cell Rep. 2015 Nov 3;13(5):898-905. doi: 10.1016/j.celrep.2015.09.057. Epub 2015 Oct 22. Cell Rep. 2015. PMID: 26565903 Free PMC article.
Melanoma metastases caught in the AKT.
Kircher DA, Arave RA, Cho JH, Holmen SL. Kircher DA, et al. Among authors: holmen sl. Mol Cell Oncol. 2016 Feb 18;3(2):e1128516. doi: 10.1080/23723556.2015.1128516. eCollection 2016 Mar. Mol Cell Oncol. 2016. PMID: 27308635 Free PMC article.
Melanoma Brain Metastasis: Mechanisms, Models, and Medicine.
Kircher DA, Silvis MR, Cho JH, Holmen SL. Kircher DA, et al. Among authors: holmen sl. Int J Mol Sci. 2016 Sep 2;17(9):1468. doi: 10.3390/ijms17091468. Int J Mol Sci. 2016. PMID: 27598148 Free PMC article. Review.
Melanoma central nervous system metastases: current approaches, challenges, and opportunities.
Cohen JV, Tawbi H, Margolin KA, Amravadi R, Bosenberg M, Brastianos PK, Chiang VL, de Groot J, Glitza IC, Herlyn M, Holmen SL, Jilaveanu LB, Lassman A, Moschos S, Postow MA, Thomas R, Tsiouris JA, Wen P, White RM, Turnham T, Davies MA, Kluger HM. Cohen JV, et al. Among authors: holmen sl. Pigment Cell Melanoma Res. 2016 Nov;29(6):627-642. doi: 10.1111/pcmr.12538. Epub 2016 Oct 22. Pigment Cell Melanoma Res. 2016. PMID: 27615400 Free PMC article. Review.
Risk factors for development of melanoma brain metastasis and disease progression: a single-center retrospective analysis.
Gardner LJ, Ward M, Andtbacka RHI, Boucher KM, Bowen GM, Bowles TL, Cohen AL, Grossmann K, Hitchcock YJ, Holmen SL, Hyngstrom J, Khong H, McMahon M, Monroe MM, Ross CB, Suneja G, Wada D, Grossman D. Gardner LJ, et al. Among authors: holmen sl. Melanoma Res. 2017 Oct;27(5):477-484. doi: 10.1097/CMR.0000000000000382. Melanoma Res. 2017. PMID: 28800031 Free PMC article.
Resistance mechanisms to genetic suppression of mutant NRAS in melanoma.
Robinson JP, Rebecca VW, Kircher DA, Silvis MR, Smalley I, Gibney GT, Lastwika KJ, Chen G, Davies MA, Grossman D, Smalley KSM, Holmen SL, VanBrocklin MW. Robinson JP, et al. Among authors: holmen sl. Melanoma Res. 2017 Dec;27(6):545-557. doi: 10.1097/CMR.0000000000000403. Melanoma Res. 2017. PMID: 29076949 Free PMC article.
Aspirin Suppresses PGE2 and Activates AMP Kinase to Inhibit Melanoma Cell Motility, Pigmentation, and Selective Tumor Growth In Vivo.
Kumar D, Rahman H, Tyagi E, Liu T, Li C, Lu R, Lum D, Holmen SL, Maschek JA, Cox JE, VanBrocklin MW, Grossman D. Kumar D, et al. Among authors: holmen sl. Cancer Prev Res (Phila). 2018 Oct;11(10):629-642. doi: 10.1158/1940-6207.CAPR-18-0087. Epub 2018 Jul 18. Cancer Prev Res (Phila). 2018. PMID: 30021726 Free PMC article.
66 results