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LKB1 and KEAP1/NRF2 Pathways Cooperatively Promote Metabolic Reprogramming with Enhanced Glutamine Dependence in KRAS-Mutant Lung Adenocarcinoma.
Galan-Cobo A, Sitthideatphaiboon P, Qu X, Poteete A, Pisegna MA, Tong P, Chen PH, Boroughs LK, Rodriguez MLM, Zhang W, Parlati F, Wang J, Gandhi V, Skoulidis F, DeBerardinis RJ, Minna JD, Heymach JV. Galan-Cobo A, et al. Among authors: qu x. Cancer Res. 2019 Jul 1;79(13):3251-3267. doi: 10.1158/0008-5472.CAN-18-3527. Epub 2019 Apr 30. Cancer Res. 2019. PMID: 31040157 Free PMC article.
STK11/LKB1 Mutations in NSCLC Are Associated with KEAP1/NRF2-Dependent Radiotherapy Resistance Targetable by Glutaminase Inhibition.
Sitthideatphaiboon P, Galan-Cobo A, Negrao MV, Qu X, Poteete A, Zhang F, Liu DD, Lewis WE, Kemp HN, Lewis J, Rinsurongkawong W, Giri U, Lee JJ, Zhang J, Roth JA, Swisher S, Heymach JV. Sitthideatphaiboon P, et al. Among authors: qu x. Clin Cancer Res. 2021 Mar 15;27(6):1720-1733. doi: 10.1158/1078-0432.CCR-20-2859. Epub 2020 Dec 15. Clin Cancer Res. 2021. PMID: 33323404 Free PMC article.
Fusobacterium Nucleatum Promotes the Development of Colorectal Cancer by Activating a Cytochrome P450/Epoxyoctadecenoic Acid Axis via TLR4/Keap1/NRF2 Signaling.
Kong C, Yan X, Zhu Y, Zhu H, Luo Y, Liu P, Ferrandon S, Kalady MF, Gao R, He J, Yin F, Qu X, Zheng J, Gao Y, Wei Q, Ma Y, Liu JY, Qin H. Kong C, et al. Among authors: qu x. Cancer Res. 2021 Sep 1;81(17):4485-4498. doi: 10.1158/0008-5472.CAN-21-0453. Epub 2021 Jun 23. Cancer Res. 2021. PMID: 34162680
Enhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado.
Galan-Cobo A, Stellrecht CM, Yilmaz E, Yang C, Qian Y, Qu X, Akhter I, Ayres ML, Fan Y, Tong P, Diao L, Ding J, Giri U, Gudikote J, Nilsson M, Wierda WG, Wang J, Skoulidis F, Minna JD, Gandhi V, Heymach JV. Galan-Cobo A, et al. Among authors: qu x. Mol Cancer Res. 2022 Feb;20(2):280-292. doi: 10.1158/1541-7786.MCR-21-0448. Epub 2021 Oct 15. Mol Cancer Res. 2022. PMID: 34654720 Free PMC article.
5,465 results