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Drug Discovery against Psoriasis: Identification of a New Potent FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor, 1-(4-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)oxy)-3-fluorophenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea, That Showed Potent Activity in a Psoriatic Animal Model.
Li GB, Ma S, Yang LL, Ji S, Fang Z, Zhang G, Wang LJ, Zhong JM, Xiong Y, Wang JH, Huang SZ, Li LL, Xiang R, Niu D, Chen YC, Yang SY. Li GB, et al. Among authors: yang sy, yang ll. J Med Chem. 2016 Sep 22;59(18):8293-305. doi: 10.1021/acs.jmedchem.6b00604. Epub 2016 Sep 2. J Med Chem. 2016. PMID: 27535613
Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model.
Li Y, Xiong Y, Zhang G, Zhang L, Yang W, Yang J, Huang L, Qiao Z, Miao Z, Lin G, Sun Q, Niu T, Chen L, Niu D, Li L, Yang S. Li Y, et al. Among authors: yang s, yang w, yang j. J Med Chem. 2018 Dec 27;61(24):11398-11414. doi: 10.1021/acs.jmedchem.8b01652. Epub 2018 Dec 10. J Med Chem. 2018. PMID: 30480444
Methyl 6-chloro-nicotinate.
Xu Y, Yang LL, Yang SY, Liu J. Xu Y, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Jan;68(Pt 1):o162. doi: 10.1107/S1600536811053517. Epub 2011 Dec 17. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22259447 Free PMC article.
Correction to Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model.
Li Y, Xiong Y, Zhang G, Zhang L, Yang W, Yang J, Huang L, Qiao Z, Miao Z, Lin G, Sun Q, Niu T, Chen L, Niu D, Li L, Yang S. Li Y, et al. Among authors: yang s, yang w, yang j. J Med Chem. 2019 Mar 28;62(6):3169. doi: 10.1021/acs.jmedchem.9b00368. Epub 2019 Mar 7. J Med Chem. 2019. PMID: 30843694 No abstract available.
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