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Will morphing boron-based inhibitors beat the β-lactamases?
Krajnc A, Lang PA, Panduwawala TD, Brem J, Schofield CJ. Krajnc A, et al. Among authors: schofield cj. Curr Opin Chem Biol. 2019 Jun;50:101-110. doi: 10.1016/j.cbpa.2019.03.001. Epub 2019 Apr 18. Curr Opin Chem Biol. 2019. PMID: 31004962 Free PMC article. Review.
Inhibitors of the FEZ-1 metallo-beta-lactamase.
Liénard BM, Horsfall LE, Galleni M, Frère JM, Schofield CJ. Liénard BM, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2007 Feb 15;17(4):964-8. doi: 10.1016/j.bmcl.2006.11.053. Epub 2006 Nov 18. Bioorg Med Chem Lett. 2007. PMID: 17157014
Mechanisms of human histone and nucleic acid demethylases.
Walport LJ, Hopkinson RJ, Schofield CJ. Walport LJ, et al. Among authors: schofield cj. Curr Opin Chem Biol. 2012 Dec;16(5-6):525-34. doi: 10.1016/j.cbpa.2012.09.015. Epub 2012 Oct 10. Curr Opin Chem Biol. 2012. PMID: 23063108 Review.
The enzymes of β-lactam biosynthesis.
Hamed RB, Gomez-Castellanos JR, Henry L, Ducho C, McDonough MA, Schofield CJ. Hamed RB, et al. Among authors: schofield cj. Nat Prod Rep. 2013 Jan;30(1):21-107. doi: 10.1039/c2np20065a. Nat Prod Rep. 2013. PMID: 23135477 Review.
Assay platform for clinically relevant metallo-β-lactamases.
van Berkel SS, Brem J, Rydzik AM, Salimraj R, Cain R, Verma A, Owens RJ, Fishwick CW, Spencer J, Schofield CJ. van Berkel SS, et al. Among authors: schofield cj. J Med Chem. 2013 Sep 12;56(17):6945-53. doi: 10.1021/jm400769b. Epub 2013 Aug 16. J Med Chem. 2013. PMID: 23898798 Free PMC article.
710 results