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Dietary supplement for mood symptoms in early postpartum: a double-blind randomized placebo controlled trial.
Meyer JH, Wang Z, Santhirakumar A, Dowlati Y, Docteur N, Shoaib A, Purnava J, Wang Y, Wang W, Chen S, Husain MI, de Silva Wijeyeratne R, Reeyaz H, Baena-Tan C, Koshimori Y, Nasser Z, Sit V. Meyer JH, et al. EClinicalMedicine. 2024 Apr 10;71:102593. doi: 10.1016/j.eclinm.2024.102593. eCollection 2024 May. EClinicalMedicine. 2024. PMID: 38813444 Free PMC article.
The supplement was designed to counter downstream effects of elevated monoamine oxidase A level, implicated in causing PPB. METHODS: Participants recruited by advertisement from the Toronto region completed procedures at CAMH, Canada and/or participants' homes. ...
The supplement was designed to counter downstream effects of elevated monoamine oxidase A level, implicated in causing PPB. ME …
Comprehensive safety evaluation of a novel multitargeting compound XYY-CP1106: A candidate for Alzheimer's disease.
Fan M, Song X, Lu L, He J, Shen Y, Zhang C, Wang F, Xie Y. Fan M, et al. Biomed Pharmacother. 2024 May 27;176:116786. doi: 10.1016/j.biopha.2024.116786. Online ahead of print. Biomed Pharmacother. 2024. PMID: 38805971
Here, the safety evaluation of a novel multi-targeted candidate in AD (XYY-CP1106), characterized by its dual-property of iron chelation and monoamine oxidase B inhibition, was conducted by multifaceted analysis. ...
Here, the safety evaluation of a novel multi-targeted candidate in AD (XYY-CP1106), characterized by its dual-property of iron chelation and …
Neurotoxic effects of carbamazepine on the mosquitofish Gambusia affinis.
Nikhil J, Maneesha P, Chitra KC. Nikhil J, et al. Drug Chem Toxicol. 2024 May 28:1-15. doi: 10.1080/01480545.2024.2356048. Online ahead of print. Drug Chem Toxicol. 2024. PMID: 38804213
Furthermore, the neurotoxic effects of carbamazepine were clearly demonstrated through alterations in various neurological parameters, including acetylcholinesterase, dopamine, gamma-aminobutyric acid, serotonin, monoamine oxidase, 5-hydroxyindole acetic acid, adren …
Furthermore, the neurotoxic effects of carbamazepine were clearly demonstrated through alterations in various neurological parameters, inclu …
Identification and optimization of nitrophenolic analogues as dopamine metabolic enzyme inhibitors for the treatment of Parkinson's disease.
Zou M, Wu Y, Lan Y, Xie H, Sun H, Liu W, Feng F, Jiang X. Zou M, et al. Bioorg Chem. 2024 May 23;148:107488. doi: 10.1016/j.bioorg.2024.107488. Online ahead of print. Bioorg Chem. 2024. PMID: 38797066
Simultaneous inhibition of the two key dopamine metabolic enzymes, catechol-O-methyltransferase (COMT) and monoamine oxidase B (MAO-B), could potentially be a breakthrough in achieving clinical efficacy. ...
Simultaneous inhibition of the two key dopamine metabolic enzymes, catechol-O-methyltransferase (COMT) and monoamine oxidase B …
Development of scoring-assisted generative exploration (SAGE) and its application to dual inhibitor design for acetylcholinesterase and monoamine oxidase B.
Lim H. Lim H. J Cheminform. 2024 May 24;16(1):59. doi: 10.1186/s13321-024-00845-w. J Cheminform. 2024. PMID: 38790018 Free PMC article.
Furthermore, I suggested a top-ranked molecule with SAGE as dual inhibitors of acetylcholinesterase and monoamine oxidase B through multiple desired property optimization. ...Additionally, the application of SAGE to discover dual inhibitors for acetylcholinesterase …
Furthermore, I suggested a top-ranked molecule with SAGE as dual inhibitors of acetylcholinesterase and monoamine oxidase B th …
Role of Vasoactive Hormone-Induced Signal Transduction in Cardiac Hypertrophy and Heart Failure.
Dhalla NS, Mota KO, Elimban V, Shah AK, de Vasconcelos CML, Bhullar SK. Dhalla NS, et al. Cells. 2024 May 17;13(10):856. doi: 10.3390/cells13100856. Cells. 2024. PMID: 38786079 Free PMC article. Review.
The prolonged exposure of the hypertrophied heart to these vasoactive hormones has been reported to result in the oxidation of catecholamines and serotonin via monoamine oxidase as well as the activation of NADPH oxidase via angiotensin II and endothelins to …
The prolonged exposure of the hypertrophied heart to these vasoactive hormones has been reported to result in the oxidation of catecholamine …
Construction of Multi-enzyme Integrated Catalysts for Deracemization of Cyclic Chiral Amines.
Zhou L, Li C, Dong L, Liu Y, He Y, Liu G, Bai J, Ma L, Jiang Y. Zhou L, et al. Chembiochem. 2024 May 22:e202400346. doi: 10.1002/cbic.202400346. Online ahead of print. Chembiochem. 2024. PMID: 38775416
In this research, we designed a four-enzyme integrated catalyst and used it to catalyse the racemization reaction of cyclic chiral amines, where monoamine oxidase (MAO) catalyses the selective oxidation of 1-methyl-1,2,3,4-tetrahydroisoquinoline (MTQ), imine reducta …
In this research, we designed a four-enzyme integrated catalyst and used it to catalyse the racemization reaction of cyclic chiral amines, w …
26,213 results
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