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Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models.
Jiménez de Oya N, Esler WP, Huard K, El-Kattan AF, Karamanlidis G, Blázquez AB, Ramos-Ibeas P, Escribano-Romero E, Louloudes-Lázaro A, Casas J, Sobrino F, Hoehn K, James DE, Gutiérrez-Adán A, Saiz JC, Martín-Acebes MA. Jiménez de Oya N, et al. Among authors: hoehn k. Emerg Microbes Infect. 2019;8(1):624-636. doi: 10.1080/22221751.2019.1604084. Emerg Microbes Infect. 2019. PMID: 30999821 Free PMC article.
Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.
Chow JD, Lawrence RT, Healy ME, Dominy JE, Liao JA, Breen DS, Byrne FL, Kenwood BM, Lackner C, Okutsu S, Mas VR, Caldwell SH, Tomsig JL, Cooney GJ, Puigserver PB, Turner N, James DE, Villén J, Hoehn KL. Chow JD, et al. Mol Metab. 2014 Mar 12;3(4):419-31. doi: 10.1016/j.molmet.2014.02.004. eCollection 2014 Jul. Mol Metab. 2014. PMID: 24944901 Free PMC article.
Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity.
Chaudhuri R, Khoo PS, Tonks K, Junutula JR, Kolumam G, Modrusan Z, Samocha-Bonet D, Meoli CC, Hocking S, Fazakerley DJ, Stöckli J, Hoehn KL, Greenfield JR, Yang JYH, James DE. Chaudhuri R, et al. Among authors: hoehn kl. NPJ Syst Biol Appl. 2015 Nov 12;1:15010. doi: 10.1038/npjsba.2015.10. eCollection 2015. NPJ Syst Biol Appl. 2015. PMID: 28725461 Free PMC article.
199 results