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Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3.
Lolli ML, Carnovale IM, Pippione AC, Wahlgren WY, Bonanni D, Marini E, Zonari D, Gallicchio M, Boscaro V, Goyal P, Friemann R, Rolando B, Bagnati R, Adinolfi S, Oliaro-Bosso S, Boschi D. Lolli ML, et al. ACS Med Chem Lett. 2019 Jan 28;10(4):437-443. doi: 10.1021/acsmedchemlett.8b00484. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996776 Free PMC article.
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid.
Pippione AC, Carnovale IM, Bonanni D, Sini M, Goyal P, Marini E, Pors K, Adinolfi S, Zonari D, Festuccia C, Wahlgren WY, Friemann R, Bagnati R, Boschi D, Oliaro-Bosso S, Lolli ML. Pippione AC, et al. Eur J Med Chem. 2018 Apr 25;150:930-945. doi: 10.1016/j.ejmech.2018.03.040. Epub 2018 Mar 16. Eur J Med Chem. 2018. PMID: 29602039
AKR1C3 is a biomarker and druggable target for oropharyngeal tumors.
Peraldo-Neia C, Ostano P, Mello-Grand M, Guana F, Gregnanin I, Boschi D, Oliaro-Bosso S, Pippione AC, Carenzo A, De Cecco L, Cavalieri S, Micali A, Perrone F, Averono G, Bagnasacco P, Dosdegani R, Masini L, Krengli M, Aluffi-Valletti P, Valente G, Chiorino G. Peraldo-Neia C, et al. Among authors: oliaro bosso s. Cell Oncol (Dordr). 2021 Apr;44(2):357-372. doi: 10.1007/s13402-020-00571-z. Epub 2020 Nov 19. Cell Oncol (Dordr). 2021. PMID: 33211282
A New Bevacizumab Carrier for Intravitreal Administration: Focus on Stability.
Chirio D, Peira E, Sapino S, Chindamo G, Oliaro-Bosso S, Adinolfi S, Dianzani C, Baratta F, Gallarate M. Chirio D, et al. Among authors: oliaro bosso s. Pharmaceutics. 2021 Apr 15;13(4):560. doi: 10.3390/pharmaceutics13040560. Pharmaceutics. 2021. PMID: 33921167 Free PMC article.
45 results