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Regulation of death receptor signaling by the autophagy protein TP53INP2.
Ivanova S, Polajnar M, Narbona-Perez AJ, Hernandez-Alvarez MI, Frager P, Slobodnyuk K, Plana N, Nebreda AR, Palacin M, Gomis RR, Behrends C, Zorzano A. Ivanova S, et al. Among authors: palacin m. EMBO J. 2019 May 15;38(10):e99300. doi: 10.15252/embj.201899300. Epub 2019 Apr 12. EMBO J. 2019. PMID: 30979779 Free PMC article.
Mfn2 modulates the UPR and mitochondrial function via repression of PERK.
Muñoz JP, Ivanova S, Sánchez-Wandelmer J, Martínez-Cristóbal P, Noguera E, Sancho A, Díaz-Ramos A, Hernández-Alvarez MI, Sebastián D, Mauvezin C, Palacín M, Zorzano A. Muñoz JP, et al. Among authors: palacin m. EMBO J. 2013 Aug 28;32(17):2348-61. doi: 10.1038/emboj.2013.168. Epub 2013 Aug 6. EMBO J. 2013. PMID: 23921556 Free PMC article.
Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway.
Sebastián D, Sorianello E, Segalés J, Irazoki A, Ruiz-Bonilla V, Sala D, Planet E, Berenguer-Llergo A, Muñoz JP, Sánchez-Feutrie M, Plana N, Hernández-Álvarez MI, Serrano AL, Palacín M, Zorzano A. Sebastián D, et al. Among authors: palacin m. EMBO J. 2016 Aug 1;35(15):1677-93. doi: 10.15252/embj.201593084. Epub 2016 Jun 22. EMBO J. 2016. PMID: 27334614 Free PMC article.
Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.
Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A. Rodríguez-Nuevo A, et al. Among authors: palacin m. EMBO J. 2018 May 15;37(10):e96553. doi: 10.15252/embj.201796553. Epub 2018 Apr 9. EMBO J. 2018. PMID: 29632021 Free PMC article.
A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells.
Segalés J, Paz JC, Hernández-Alvarez MI, Sala D, Muñoz JP, Noguera E, Pich S, Palacín M, Enríquez JA, Zorzano A. Segalés J, et al. Among authors: palacin m. Am J Physiol Endocrinol Metab. 2013 Nov 15;305(10):E1208-21. doi: 10.1152/ajpendo.00546.2012. Epub 2013 Aug 13. Am J Physiol Endocrinol Metab. 2013. PMID: 23941871 Free article.
334 results