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Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα.
Liang N, Damdimopoulos A, Goñi S, Huang Z, Vedin LL, Jakobsson T, Giudici M, Ahmed O, Pedrelli M, Barilla S, Alzaid F, Mendoza A, Schröder T, Kuiper R, Parini P, Hollenberg A, Lefebvre P, Francque S, Van Gaal L, Staels B, Venteclef N, Treuter E, Fan R. Liang N, et al. Among authors: damdimopoulos a. Nat Commun. 2019 Apr 11;10(1):1684. doi: 10.1038/s41467-019-09524-z. Nat Commun. 2019. PMID: 30975991 Free PMC article.
G protein pathway suppressor 2 (GPS2) links inflammation and cholesterol efflux by controlling lipopolysaccharide-induced ATP-binding cassette transporter A1 expression in macrophages.
Huang Z, Liang N, Damdimopoulos A, Fan R, Treuter E. Huang Z, et al. Among authors: damdimopoulos a. FASEB J. 2019 Feb;33(2):1631-1643. doi: 10.1096/fj.201801123R. Epub 2018 Aug 28. FASEB J. 2019. PMID: 30153049
Of particular relevance is that the expression of ATP-binding cassette transporter A1 ( Abca1), a main regulator of cholesterol efflux, can be induced by oxysterol receptor LXR agonists but also by bacterial endotoxins, such as LPS, that activate TLR4 signaling. ...Because …
Of particular relevance is that the expression of ATP-binding cassette transporter A1 ( Abca1), a main regulator of cholesterol efflu …
Effects of chemical in vitro activation versus fragmentation on human ovarian tissue and follicle growth in culture.
Hao J, Li T, Heinzelmann M, Moussaud-Lamodière E, Lebre F, Krjutškov K, Damdimopoulos A, Arnelo C, Pettersson K, Alfaro-Moreno E, Lindskog C, van Duursen M, Damdimopoulou P. Hao J, et al. Among authors: damdimopoulos a. Hum Reprod Open. 2024 May 22;2024(3):hoae028. doi: 10.1093/hropen/hoae028. eCollection 2024. Hum Reprod Open. 2024. PMID: 38803550 Free PMC article.
Exposure to the phthalate metabolite MEHP impacts survival and growth of human ovarian follicles in vitro.
Panagiotou EM, Damdimopoulos A, Li T, Moussaud-Lamodière E, Pedersen M, Lebre F, Pettersson K, Arnelo C, Papaikonomou K, Alfaro-Moreno E, Lindskog C, Svingen T, Damdimopoulou P. Panagiotou EM, et al. Among authors: damdimopoulos a. Toxicology. 2024 Apr 27;505:153815. doi: 10.1016/j.tox.2024.153815. Online ahead of print. Toxicology. 2024. PMID: 38685446 Free article.
Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF.
Kvedaraite E, Lourda M, Mouratidou N, Düking T, Padhi A, Moll K, Czarnewski P, Sinha I, Xagoraris I, Kokkinou E, Damdimopoulos A, Weigel W, Hartwig O, Santos TE, Soini T, Van Acker A, Rahkonen N, Flodström Tullberg M, Ringqvist E, Buggert M, Jorns C, Lindforss U, Nordenvall C, Stamper CT, Unnersjö-Jess D, Akber M, Nadisauskaite R, Jansson J, Vandamme N, Sorini C, Grundeken ME, Rolandsdotter H, Rassidakis G, Villablanca EJ, Ideström M, Eulitz S, Arnell H, Mjösberg J, Henter JI, Svensson M. Kvedaraite E, et al. Among authors: damdimopoulos a. Nat Commun. 2024 Feb 26;15(1):1752. doi: 10.1038/s41467-024-46076-3. Nat Commun. 2024. PMID: 38409190 Free PMC article.
Transcriptional determinants of lipid mobilization in human adipocytes.
Ludzki AC, Hansen M, Zareifi D, Jalkanen J, Huang Z, Omar-Hmeadi M, Renzi G, Klingelhuber F, Boland S, Ambaw YA, Wang N, Damdimopoulos A, Liu J, Jernberg T, Petrus P, Arner P, Krahmer N, Fan R, Treuter E, Gao H, Rydén M, Mejhert N. Ludzki AC, et al. Among authors: damdimopoulos a. Sci Adv. 2024 Jan 5;10(1):eadi2689. doi: 10.1126/sciadv.adi2689. Epub 2024 Jan 3. Sci Adv. 2024. PMID: 38170777 Free PMC article.
Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro.
Tarvainen I, Soto DA, Laws MJ, Björvang RD, Damdimopoulos A, Roos K, Li T, Kramer S, Li Z, Lavogina D, Visser N, Kallak TK, Lager S, Gidlöf S, Edlund E, Papaikonomou K, Öberg M, Olovsson M, Salumets A, Velthut-Meikas A, Flaws JA, Damdimopoulou P. Tarvainen I, et al. Among authors: damdimopoulos a. Reprod Toxicol. 2023 Aug;119:108393. doi: 10.1016/j.reprotox.2023.108393. Epub 2023 May 7. Reprod Toxicol. 2023. PMID: 37160244 Free article.
60 results