Kang Y - Search Results

1

Structure and dynamics of the active human parathyroid hormone receptor-1.

Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, Li C, Jiang Y, Watanabe T, Gardella TJ, Melcher K, Wang MW, Vilardaga JP, Xu HE, Zhang Y. Zhao LH, et al. Among authors: kang y. Science. 2019 Apr 12;364(6436):148-153. doi: 10.1126/science.aav7942. Science. 2019. PMID: 30975883 Free PMC article.

2

The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer.

Liu P, Jia MZ, Zhou XE, De Waal PW, Dickson BM, Liu B, Hou L, Yin YT, Kang YY, Shi Y, Melcher K, Xu HE, Jiang Y. Liu P, et al. Among authors: kang yy. Acta Pharmacol Sin. 2016 Sep;37(9):1259-72. doi: 10.1038/aps.2016.69. Epub 2016 Aug 8. Acta Pharmacol Sin. 2016. PMID: 27498775 Free PMC article.

3

The cryo-electron microscopy structure of γ-Secretase: towards complex assembly, substrate recognition and a catalytic mechanism.

Kang Y, Melcher K, Xu HE. Kang Y, et al. Natl Sci Rev. 2015 Mar 1;2(1):4-5. doi: 10.1093/nsr/nwu081. Natl Sci Rev. 2015. PMID: 26090270 Free PMC article. No abstract available.

4

A structural snapshot of the rhodopsin-arrestin complex.

Kang Y, Gao X, Zhou XE, He Y, Melcher K, Xu HE. Kang Y, et al. FEBS J. 2016 Mar;283(5):816-21. doi: 10.1111/febs.13561. Epub 2015 Nov 7. FEBS J. 2016. PMID: 26467309 Free PMC article. Review.

5

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.

Kang Y, Kuybeda O, de Waal PW, Mukherjee S, Van Eps N, Dutka P, Zhou XE, Bartesaghi A, Erramilli S, Morizumi T, Gu X, Yin Y, Liu P, Jiang Y, Meng X, Zhao G, Melcher K, Ernst OP, Kossiakoff AA, Subramaniam S, Xu HE. Kang Y, et al. Nature. 2018 Jun;558(7711):553-558. doi: 10.1038/s41586-018-0215-y. Epub 2018 Jun 13. Nature. 2018. PMID: 29899450 Free PMC article.

6

Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.

Dutka P, Mukherjee S, Gao X, Kang Y, de Waal PW, Wang L, Zhuang Y, Melcher K, Zhang C, Xu HE, Kossiakoff AA. Dutka P, et al. Among authors: kang y. Structure. 2019 Dec 3;27(12):1862-1874.e7. doi: 10.1016/j.str.2019.10.004. Epub 2019 Oct 25. Structure. 2019. PMID: 31669042 Free PMC article.

7

Structure of formylpeptide receptor 2-G_i complex reveals insights into ligand recognition and signaling.

Zhuang Y, Liu H, Edward Zhou X, Kumar Verma R, de Waal PW, Jang W, Xu TH, Wang L, Meng X, Zhao G, Kang Y, Melcher K, Fan H, Lambert NA, Eric Xu H, Zhang C. Zhuang Y, et al. Among authors: kang y. Nat Commun. 2020 Feb 14;11(1):885. doi: 10.1038/s41467-020-14728-9. Nat Commun. 2020. PMID: 32060286 Free PMC article.

8

Structure of a PLS-class pentatricopeptide repeat protein provides insights into mechanism of RNA recognition.

Ban T, Ke J, Chen R, Gu X, Tan MH, Zhou XE, Kang Y, Melcher K, Zhu JK, Xu HE. Ban T, et al. Among authors: kang y. J Biol Chem. 2013 Nov 1;288(44):31540-8. doi: 10.1074/jbc.M113.496828. Epub 2013 Sep 18. J Biol Chem. 2013. PMID: 24047899 Free PMC article.

9

Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.

Kang Y, Kuybeda O, de Waal PW, Mukherjee S, Van Eps N, Dutka P, Zhou XE, Bartesaghi A, Erramilli S, Morizumi T, Gu X, Yin Y, Liu P, Jiang Y, Meng X, Zhao G, Melcher K, Ernst OP, Kossiakoff AA, Subramaniam S, Xu HE. Kang Y, et al. Nature. 2018 Sep;561(7724):E44. doi: 10.1038/s41586-018-0302-0. Nature. 2018. PMID: 29930353

10

Alzheimer's disease-associated mutations increase amyloid precursor protein resistance to γ-secretase cleavage and the Aβ42/Aβ40 ratio.

Xu TH, Yan Y, Kang Y, Jiang Y, Melcher K, Xu HE. Xu TH, et al. Among authors: kang y. Cell Discov. 2016 Aug 23;2:16026. doi: 10.1038/celldisc.2016.26. eCollection 2016. Cell Discov. 2016. PMID: 27625790 Free PMC article.

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