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A Phase 1 trial of autologous monocytes stimulated ex vivo with Sylatron® (Peginterferon alfa-2b) and Actimmune® (Interferon gamma-1b) for intra-peritoneal administration in recurrent ovarian cancer.
Green DS, Nunes AT, David-Ocampo V, Ekwede IB, Houston ND, Highfill SL, Khuu H, Stroncek DF, Steinberg SM, Zoon KC, Annunziata CM. Green DS, et al. Among authors: highfill sl. J Transl Med. 2018 Jul 16;16(1):196. doi: 10.1186/s12967-018-1569-5. J Transl Med. 2018. PMID: 30012146 Free PMC article. Clinical Trial.
Production of a cellular product consisting of monocytes stimulated with Sylatron® (Peginterferon alfa-2b) and Actimmune® (Interferon gamma-1b) for human use.
Green DS, Nunes AT, Tosh KW, David-Ocampo V, Fellowes VS, Ren J, Jin J, Frodigh SE, Pham C, Procter J, Tran C, Ekwede I, Khuu H, Stroncek DF, Highfill SL, Zoon KC, Annunziata CM. Green DS, et al. Among authors: highfill sl. J Transl Med. 2019 Mar 14;17(1):82. doi: 10.1186/s12967-019-1822-6. J Transl Med. 2019. PMID: 30871636 Free PMC article.
Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence.
Ramakrishna S, Highfill SL, Walsh Z, Nguyen SM, Lei H, Shern JF, Qin H, Kraft IL, Stetler-Stevenson M, Yuan CM, Hwang JD, Feng Y, Zhu Z, Dimitrov D, Shah NN, Fry TJ. Ramakrishna S, et al. Among authors: highfill sl. Clin Cancer Res. 2019 Sep 1;25(17):5329-5341. doi: 10.1158/1078-0432.CCR-18-3784. Epub 2019 May 20. Clin Cancer Res. 2019. PMID: 31110075 Free PMC article.
Effect of Cryopreservation on Autologous Chimeric Antigen Receptor T Cell Characteristics.
Panch SR, Srivastava SK, Elavia N, McManus A, Liu S, Jin P, Highfill SL, Li X, Dagur P, Kochenderfer JN, Fry TJ, Mackall CL, Lee D, Shah NN, Stroncek DF. Panch SR, et al. Among authors: highfill sl. Mol Ther. 2019 Jul 3;27(7):1275-1285. doi: 10.1016/j.ymthe.2019.05.015. Epub 2019 May 30. Mol Ther. 2019. PMID: 31178392 Free PMC article.
60 results