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Development of an anti-BAG3 humanized antibody for treatment of pancreatic cancer.
Basile A, De Marco M, Festa M, Falco A, Iorio V, Guerriero L, Eletto D, Rea D, Arra C, Lamolinara A, Ballerini P, Damiani V, Rosati A, Sala G, Turco MC, Marzullo L, De Laurenzi V. Basile A, et al. Among authors: arra c. Mol Oncol. 2019 Jun;13(6):1388-1399. doi: 10.1002/1878-0261.12492. Epub 2019 May 17. Mol Oncol. 2019. PMID: 30973679 Free PMC article.
The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand.
Chiappetta G, Ammirante M, Basile A, Rosati A, Festa M, Monaco M, Vuttariello E, Pasquinelli R, Arra C, Zerilli M, Todaro M, Stassi G, Pezzullo L, Gentilella A, Tosco A, Pascale M, Marzullo L, Belisario MA, Turco MC, Leone A. Chiappetta G, et al. Among authors: arra c. J Clin Endocrinol Metab. 2007 Mar;92(3):1159-63. doi: 10.1210/jc.2006-1712. Epub 2006 Dec 12. J Clin Endocrinol Metab. 2007. PMID: 17164298
IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth.
Ammirante M, Rosati A, Arra C, Basile A, Falco A, Festa M, Pascale M, d'Avenia M, Marzullo L, Belisario MA, De Marco M, Barbieri A, Giudice A, Chiappetta G, Vuttariello E, Monaco M, Bonelli P, Salvatore G, Di Benedetto M, Deshmane SL, Khalili K, Turco MC, Leone A. Ammirante M, et al. Among authors: arra c. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7497-502. doi: 10.1073/pnas.0907696107. Epub 2010 Apr 5. Proc Natl Acad Sci U S A. 2010. PMID: 20368414 Free PMC article.
Role of endothelial nitric oxide synthase (eNOS) in chronic stress-promoted tumour growth.
Barbieri A, Palma G, Rosati A, Giudice A, Falco A, Petrillo A, Petrillo M, Bimonte S, Di Benedetto M, Esposito G, Stiuso P, Abbruzzese A, Caraglia M, Arra C. Barbieri A, et al. Among authors: arra c. J Cell Mol Med. 2012 Apr;16(4):920-6. doi: 10.1111/j.1582-4934.2011.01375.x. J Cell Mol Med. 2012. PMID: 21722303 Free PMC article.
BAG3 down-modulation reduces anaplastic thyroid tumor growth by enhancing proteasome-mediated degradation of BRAF protein.
Chiappetta G, Basile A, Arra C, Califano D, Pasquinelli R, Barbieri A, De Simone V, Rea D, Giudice A, Pezzullo L, De Laurenzi V, Botti G, Losito S, Conforti D, Turco MC. Chiappetta G, et al. Among authors: arra c. J Clin Endocrinol Metab. 2012 Jan;97(1):E115-20. doi: 10.1210/jc.2011-0484. Epub 2011 Nov 9. J Clin Endocrinol Metab. 2012. PMID: 22072743
171 results