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NanoBRET: The Bright Future of Proximity-Based Assays.
Dale NC, Johnstone EKM, White CW, Pfleger KDG. Dale NC, et al. Among authors: pfleger kdg. Front Bioeng Biotechnol. 2019 Mar 26;7:56. doi: 10.3389/fbioe.2019.00056. eCollection 2019. Front Bioeng Biotechnol. 2019. PMID: 30972335 Free PMC article. Review.
Application of BRET to monitor ligand binding to GPCRs.
Stoddart LA, Johnstone EKM, Wheal AJ, Goulding J, Robers MB, Machleidt T, Wood KV, Hill SJ, Pfleger KDG. Stoddart LA, et al. Among authors: pfleger kdg. Nat Methods. 2015 Jul;12(7):661-663. doi: 10.1038/nmeth.3398. Epub 2015 Jun 1. Nat Methods. 2015. PMID: 26030448 Free PMC article.
BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes.
O'Brien SL, Johnstone EKM, Devost D, Conroy J, Reichelt ME, Purdue BW, Ayoub MA, Kawai T, Inoue A, Eguchi S, Hébert TE, Pfleger KDG, Thomas WG. O'Brien SL, et al. Among authors: pfleger kdg. Biochem Pharmacol. 2018 Dec;158:232-242. doi: 10.1016/j.bcp.2018.10.017. Epub 2018 Oct 19. Biochem Pharmacol. 2018. PMID: 30347205 Free PMC article.
73 results