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Production of Epoxyketone Peptide-Based Proteasome Inhibitors by Streptomyces sp. BRA-346: Regulation and Biosynthesis.
Domingues Vieira B, Niero H, de Felício R, Giolo Alves LF, Freitas Bazzano C, Sigrist R, Costa Furtado L, Felix Persinoti G, Veras Costa-Lotufo L, Barretto Barbosa Trivella D. Domingues Vieira B, et al. Among authors: sigrist r. Front Microbiol. 2022 Mar 24;13:786008. doi: 10.3389/fmicb.2022.786008. eCollection 2022. Front Microbiol. 2022. PMID: 35401454 Free PMC article.
Nature-inspired enzymatic cascades to build valuable compounds.
Sigrist R, da Costa BZ, Marsaioli AJ, de Oliveira LG. Sigrist R, et al. Biotechnol Adv. 2015 Sep-Oct;33(5):394-411. doi: 10.1016/j.biotechadv.2015.03.010. Epub 2015 Mar 18. Biotechnol Adv. 2015. PMID: 25795056 Review.
Chemical Elicitors Induce Rare Bioactive Secondary Metabolites in Deep-Sea Bacteria under Laboratory Conditions.
de Felício R, Ballone P, Bazzano CF, Alves LFG, Sigrist R, Infante GP, Niero H, Rodrigues-Costa F, Fernandes AZN, Tonon LAC, Paradela LS, Costa RKE, Dias SMG, Dessen A, Telles GP, da Silva MAC, Lima AOS, Trivella DBB. de Felício R, et al. Among authors: sigrist r. Metabolites. 2021 Feb 12;11(2):107. doi: 10.3390/metabo11020107. Metabolites. 2021. PMID: 33673148 Free PMC article.
Maramycin, a Cytotoxic Isoquinolinequinone Terpenoid Produced through Heterologous Expression of a Bifunctional Indole Prenyltransferase/Tryptophan Indole-Lyase in S. albidoflavus.
Maleckis M, Wibowo M, Williams SE, Gotfredsen CH, Sigrist R, Souza LDO, Cowled MS, Charusanti P, Gren T, Saha S, Moreira JMA, Weber T, Ding L. Maleckis M, et al. Among authors: sigrist r. ACS Chem Biol. 2024 May 14. doi: 10.1021/acschembio.4c00121. Online ahead of print. ACS Chem Biol. 2024. PMID: 38743035
52 results