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The lipid droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4.
Jebessa ZH, Shanmukha KD, Dewenter M, Lehmann LH, Xu C, Schreiter F, Siede D, Gong XM, Worst BC, Federico G, Sauer SW, Fischer T, Wechselberger L, Müller OJ, Sossalla S, Dieterich C, Most P, Gröne HJ, Moro C, Oberer M, Haemmerle G, Katus HA, Tyedmers J, Backs J. Jebessa ZH, et al. Nat Metab. 2019 Nov;1(11):1157-1167. doi: 10.1038/s42255-019-0138-4. Epub 2019 Nov 15. Nat Metab. 2019. PMID: 31742248 Free PMC article.
CaM Kinase II mediates maladaptive post-infarct remodeling and pro-inflammatory chemoattractant signaling but not acute myocardial ischemia/reperfusion injury.
Weinreuter M, Kreusser MM, Beckendorf J, Schreiter FC, Leuschner F, Lehmann LH, Hofmann KP, Rostosky JS, Diemert N, Xu C, Volz HC, Jungmann A, Nickel A, Sticht C, Gretz N, Maack C, Schneider MD, Gröne HJ, Müller OJ, Katus HA, Backs J. Weinreuter M, et al. Among authors: schreiter fc. EMBO Mol Med. 2014 Oct;6(10):1231-45. doi: 10.15252/emmm.201403848. EMBO Mol Med. 2014. PMID: 25193973 Free PMC article.
CaM Kinase II-δ Is Required for Diabetic Hyperglycemia and Retinopathy but Not Nephropathy.
Chen J, Fleming T, Katz S, Dewenter M, Hofmann K, Saadatmand A, Kronlage M, Werner MP, Pokrandt B, Schreiter F, Lin J, Katz D, Morgenstern J, Elwakiel A, Sinn P, Gröne HJ, Hammes HP, Nawroth PP, Isermann B, Sticht C, Brügger B, Katus HA, Hagenmueller M, Backs J. Chen J, et al. Diabetes. 2021 Feb;70(2):616-626. doi: 10.2337/db19-0659. Epub 2020 Nov 25. Diabetes. 2021. PMID: 33239449