Bohr VA - Search Results

1

Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model.

Zhang P, Kishimoto Y, Grammatikakis I, Gottimukkala K, Cutler RG, Zhang S, Abdelmohsen K, Bohr VA, Misra Sen J, Gorospe M, Mattson MP. Zhang P, et al. Among authors: bohr va. Nat Neurosci. 2019 May;22(5):719-728. doi: 10.1038/s41593-019-0372-9. Epub 2019 Apr 1. Nat Neurosci. 2019. PMID: 30936558 Free PMC article.

2

TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons.

Zhang P, Furukawa K, Opresko PL, Xu X, Bohr VA, Mattson MP. Zhang P, et al. Among authors: bohr va. J Neurochem. 2006 Apr;97(2):567-81. doi: 10.1111/j.1471-4159.2006.03779.x. Epub 2006 Mar 15. J Neurochem. 2006. PMID: 16539655 Free article.

3

Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment.

Weissman L, Jo DG, Sørensen MM, de Souza-Pinto NC, Markesbery WR, Mattson MP, Bohr VA. Weissman L, et al. Among authors: bohr va. Nucleic Acids Res. 2007;35(16):5545-55. doi: 10.1093/nar/gkm605. Epub 2007 Aug 17. Nucleic Acids Res. 2007. PMID: 17704129 Free PMC article.

4

DNA base excision repair activities in mouse models of Alzheimer's disease.

Weissman L, de Souza-Pinto NC, Mattson MP, Bohr VA. Weissman L, et al. Among authors: bohr va. Neurobiol Aging. 2009 Dec;30(12):2080-1. doi: 10.1016/j.neurobiolaging.2008.02.014. Epub 2008 Apr 18. Neurobiol Aging. 2009. PMID: 18378358 Free PMC article.

5

Mitochondrial DNA damage and repair in neurodegenerative disorders.

Yang JL, Weissman L, Bohr VA, Mattson MP. Yang JL, et al. Among authors: bohr va. DNA Repair (Amst). 2008 Jul 1;7(7):1110-20. doi: 10.1016/j.dnarep.2008.03.012. Epub 2008 May 7. DNA Repair (Amst). 2008. PMID: 18463003 Free PMC article. Review.

6

Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1.

Yang JL, Tadokoro T, Keijzers G, Mattson MP, Bohr VA. Yang JL, et al. Among authors: bohr va. J Biol Chem. 2010 Sep 3;285(36):28191-9. doi: 10.1074/jbc.M109.082883. Epub 2010 Jun 23. J Biol Chem. 2010. PMID: 20573957 Free PMC article.

7

Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions.

Liu D, Croteau DL, Souza-Pinto N, Pitta M, Tian J, Wu C, Jiang H, Mustafa K, Keijzers G, Bohr VA, Mattson MP. Liu D, et al. Among authors: bohr va. J Cereb Blood Flow Metab. 2011 Feb;31(2):680-92. doi: 10.1038/jcbfm.2010.147. Epub 2010 Aug 25. J Cereb Blood Flow Metab. 2011. PMID: 20736962 Free PMC article.

8

The excitatory neurotransmitter glutamate stimulates DNA repair to increase neuronal resiliency.

Yang JL, Sykora P, Wilson DM 3rd, Mattson MP, Bohr VA. Yang JL, et al. Among authors: bohr va. Mech Ageing Dev. 2011 Aug;132(8-9):405-11. doi: 10.1016/j.mad.2011.06.005. Epub 2011 Jun 25. Mech Ageing Dev. 2011. PMID: 21729715 Free PMC article. Review.

9

SRT1720 improves survival and healthspan of obese mice.

Minor RK, Baur JA, Gomes AP, Ward TM, Csiszar A, Mercken EM, Abdelmohsen K, Shin YK, Canto C, Scheibye-Knudsen M, Krawczyk M, Irusta PM, Martín-Montalvo A, Hubbard BP, Zhang Y, Lehrmann E, White AA, Price NL, Swindell WR, Pearson KJ, Becker KG, Bohr VA, Gorospe M, Egan JM, Talan MI, Auwerx J, Westphal CH, Ellis JL, Ungvari Z, Vlasuk GP, Elliott PJ, Sinclair DA, de Cabo R. Minor RK, et al. Among authors: bohr va. Sci Rep. 2011;1:70. doi: 10.1038/srep00070. Epub 2011 Aug 18. Sci Rep. 2011. PMID: 22355589 Free PMC article.

10

Endonuclease VIII-like 1 (NEIL1) promotes short-term spatial memory retention and protects from ischemic stroke-induced brain dysfunction and death in mice.

Canugovi C, Yoon JS, Feldman NH, Croteau DL, Mattson MP, Bohr VA. Canugovi C, et al. Among authors: bohr va. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14948-53. doi: 10.1073/pnas.1204156109. Epub 2012 Aug 27. Proc Natl Acad Sci U S A. 2012. PMID: 22927410 Free PMC article.

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