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Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer.
J Med Chem. 2019 Apr 25;62(8):4120-4130. doi: 10.1021/acs.jmedchem.9b00178. Epub 2019 Apr 12.
J Med Chem. 2019.
PMID: 30933499
Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8.
Judge RA, Zhu H, Upadhyay AK, Bodelle PM, Hutchins CW, Torrent M, Marin VL, Yu W, Vedadi M, Li F, Brown PJ, Pappano WN, Sun C, Petros AM.
Judge RA, et al. Among authors: bodelle pm.
ACS Med Chem Lett. 2016 Oct 11;7(12):1102-1106. doi: 10.1021/acsmedchemlett.6b00303. eCollection 2016 Dec 8.
ACS Med Chem Lett. 2016.
PMID: 27994746
Free PMC article.
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Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain - A fragment based approach.
Upadhyay AK, Judge RA, Li L, Pithawalla R, Simanis J, Bodelle PM, Marin VL, Henry RF, Petros AM, Sun C.
Upadhyay AK, et al. Among authors: bodelle pm.
Bioorg Med Chem Lett. 2018 Jun 1;28(10):1708-1713. doi: 10.1016/j.bmcl.2018.04.050. Epub 2018 Apr 19.
Bioorg Med Chem Lett. 2018.
PMID: 29691138
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Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site.
Goedken ER, Argiriadi MA, Dietrich JD, Petros AM, Krishnan N, Panchal SC, Qiu W, Wu H, Zhu H, Adams AM, Bodelle PM, Goguen L, Richardson PL, Slivka PF, Srikumaran M, Upadhyay AK, Wu B, Judge RA, Vasudevan A, Gopalakrishnan SM, Cox PB, Stoll VS, Sun C.
Goedken ER, et al. Among authors: bodelle pm.
Sci Rep. 2022 Aug 26;12(1):14561. doi: 10.1038/s41598-022-18760-1.
Sci Rep. 2022.
PMID: 36028520
Free PMC article.
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